Merck's oral HIV treatment non-inferior to Gilead's Biktarvy in late-stage trial

Reuters
2025.11.19 13:32
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Merck's experimental oral HIV treatment, combining doravirine and islatravir, proved non-inferior to Gilead's Biktarvy in a late-stage trial for adults with HIV-1 who hadn't received prior treatment. The safety profile was comparable, and Merck plans to present detailed findings at a medical meeting and submit applications to health authorities. The FDA decision on approval is expected by April 28, 2026. Doravirine is already approved in the U.S., while islatravir is still experimental.