NASDAQ Composite Index has rose 0.59%, with a year-to-date rose 21.2%; S&amp;P 500 has rose 0.25%, with a year-to-date rose 16.1%; Dow Jones Industrial Average has rose 0.39%, with a year-to-date rose 11.6%.Janux Therapeutics(JANX) fell 53.34%, with a trading turnover 271.2 Million USD, and a year-to-date fell 70.4%.
American Bitcoin(ABTC) fell 38.83%, with a trading turnover 185.4 Million USD, and a year-to-date rose 9.3%.
Symbotic(SYM) fell 21.51%, with a trading turnover 515.4 Million USD, and a year-to-date rose 182.4%.<img src="https://pub.pbkrs.com/screenshot/us_decrease_top_ten_2025-12-03_en-1764712840996061166.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_decrease_top_ten_2025-12-03_en-1764712840996061166.png"/>

JANX

ABTC

IREN

ALAB

CIFR

XPEV

WULF

Janux Therapeutics(JANX) fell 53.34%, with a trading turnover 271.2 Million USD, and a year-to-date fell 70.4%. American Bitcoin(ABTC) fell 38.83%, with a trading turnover 185.4 Million USD, and a year-to-date rose 9.3%. Symbotic(SYM) fell 21.51%, with a trading turnover 515.4 Million USD, and a year-to-date rose 182.4%.

- The Nasdaq Composite Index rose by 0.59%, with a year-to-date increase of 21.2%.  
- The S&P 500 Index increased by 0.25%, accumulating a 16.1% rise this year, while the Dow Jones Index gained 0.39% for an 11.6% year-to-date increase.  
- In contrast, Janux Therapeutics fell by 53.34%, American Bitcoin dropped by 38.83%, and Symbotic decreased by 21.51%, with respective year-to-date changes of -70.4%, +9.3%, and +182.4%.  

Top 10 US Stock Losers (12.2)