<div id="readability-page-1"><div><p><span>O'Keefe Kenneth W Director of Jazz Pharmaceuticals Plc [JAZZ] filed a Form 4 on December 4, 2025 with the Securities and Exchange Commission disclosing the following changes in ownership:</span></p><div><table><tbody><tr><td><span>Date</span></td><td><span>12/2/25</span></td></tr><tr><td><span>Transaction</span></td><td><span>Surrender(1)</span></td></tr><tr><td><span>Shares</span></td><td><span>603</span></td></tr><tr><td><span>Price</span></td><td><span>$173.07</span></td></tr><tr><td><span>Value</span></td><td><span>$104,361</span></td></tr></tbody></table></div><p><span>Ending Holdings: 30,256 (25,811 - Direct, 4,445 - Indirect)</span></p><ul><li><span>(1)</span></li><li><span>Surrender of shares back to company to pay option exercise cost and/or resulting tax liability.</span></li></ul><p><span>For a free trial, or to learn more about our insider trading analysis and data services, please visit http://www.washingtonservice.com or contact us at (301) 913-5100 or send an email to info@washingtonservice.com.</span></p><p><span>Founded in 1970, The Washington Service provides securities professionals with financial, economic and public policy research and data.</span></p><span> </span></div></div>

JAZZ

<p>Director Kenneth W. O'Keefe of Jazz Pharmaceuticals Plc surrendered 603 shares back to the company to cover option exercise costs and/or tax liabilities. The transaction was filed with the SEC on December 4, 2025, at a price of $173.07 per share, totaling $104,361. O'Keefe's ending holdings are 30,256 shares, with 25,811 direct and 4,445 indirect.</p>

Dir O'Keefe Surrenders 603 Of Jazz Pharmaceuticals Plc [JAZZ]