
Deciphera Announces Oral Presentation of Positive Topline Results from Phase 2a Study of Sapablursen in Polycythemia Vera at the 67th American Society of Hematology (ASH) Annual Meeting

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Deciphera Pharmaceuticals announced positive results from the Phase 2a IMPRSSION study of sapablursen in polycythemia vera at the ASH Annual Meeting. The study showed sapablursen significantly reduced phlebotomy rates, controlled hematocrit, and increased serum hepcidin. Sapablursen was safe and well tolerated, supporting further development in a Phase 3 study. Sapablursen has received Fast Track, orphan drug, and Breakthrough Therapy designations from the FDA. Deciphera plans to initiate a Phase 3 study in 2026.

