<div id="readability-page-1"><article>MOCKSVILLE, N.C., Dec. 09, 2025 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company that has for 27 years led and continues to lead the fight against the harms of smoking driven by nicotine addiction, today announced that Larry Firestone, Chief Executive Officer, will present as part of the Emerging Growth Virtual Investor Conference taking place on Wednesday, December 10, 2025. The Company’s update presentation will take place at 3:55 PM Eastern Time. Investors can register to attend online at: https://goto.webcasts.com/starthere.jsp?ei=1717093&amp;tp_key=e9cb5d164a&amp;sti=xxii. Investors may submit questions in advance to Questions@EmergingGrowth.com for consideration as part of the webcast event, time permitting. If attendees are not able to join the event live on the day of the conference, an archived webcast will also be made available in the Events section on 22nd Century’s Investor Relations website at https://ir.xxiicentury.com/events. <div>About 22nd Century Group, Inc.22nd Century Group is pioneering the tobacco harm reduction movement by enabling smokers to take control of their nicotine consumption.</div> <div>Our Technology is TobaccoOur proprietary non-GMO reduced nicotine tobacco plants were developed using our patented technologies that regulate alkaloid biosynthesis activities resulting in a tobacco plant that contains 95% less nicotine than traditional tobacco plants. Our extensive patent portfolio has been developed to ensure that our high-quality tobacco can be grown commercially at scale. We continue to develop our intellectual property to ensure our ongoing leadership in the tobacco harm reduction movement.</div> Our Products We created our flagship product, the VLN® cigarette using our low nicotine tobacco, to give traditional cigarette smokers an authentic and familiar alternative in the form of a combustible cigarette that helps them take control of their nicotine consumption. VLN® cigarettes have 95% less nicotine compared to traditional cigarettes and have been proven to allow consumers to greatly reduce their nicotine consumption. FDA Authorized Our VLN® cigarette is the only low nicotine combustible cigarette authorized by the FDA in the United States. VLN® is a registered trademark of 22nd Century Limited LLC. Learn more at xxiicentury.com, on X (formerly Twitter), on LinkedIn, and on YouTube. Learn more about VLN® at tryvln.com. Cautionary Note Regarding Forward-Looking Statements Except for historical information, all of the statements, expectations, and assumptions contained in this press release are forward-looking statements, including but not limited to our full year business outlook. Forward-looking statements typically contain terms such as “anticipate,” “believe,” “consider,” “continue,” “could,” “estimate,” “expect,” “explore,” “foresee,” “goal,” “guidance,” “intend,” “likely,” “may,” “plan,” “potential,” “predict,” “preliminary,” “probable,” “project,” “promising,” “seek,” “should,” “will,” “would,” and similar expressions. Forward-looking statements include, but are not limited to, statements regarding (i) our cost reduction initiatives, (ii) our expectations regarding regulatory enforcement, including our ability to receive an exemption from new regulations, and (iii) our financial and operating performance. Actual results might differ materially from those explicit or implicit in forward-looking statements. Important factors that could cause actual results to differ materially are set forth in “Risk Factors” in the Company’s Annual Report on Form 10-K filed on March 20, 2025 and Quarterly Reports on Form 10-Q on May 13, 2025, August 14, 2025, and November 4, 2025. All information provided in this release is as of the date hereof, and the Company assumes no obligation to and does not intend to update these forward-looking statements, except as required by law. Investor Relations &amp; Media Contact Matt Kreps Investor Relations 22nd Century Group investorrelations@xxiicentury.com 214-597-8200 <img src="https://imageproxy.pbkrs.com/https://www.globenewswire.com/newsroom/ti/query-bmY9T1RVNU9UTTBOeU0zTXpFek5UVXhJelV3TURFek1UUTROQT09?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="1" height="1" original-src="https://imageproxy.pbkrs.com/https://www.globenewswire.com/newsroom/ti/query-bmY9T1RVNU9UTTBOeU0zTXpFek5UVXhJelV3TURFek1UUTROQT09"/> <img src="https://imageproxy.pbkrs.com/https://ml.globenewswire.com/media/MTRiOTZjNmQtOGEwMS00MzU1LWI1ODQtNmMxNDIxOTk5YjlmLTUwMDEzMTQ4NC0yMDI1LTEyLTA5LWVu/tiny/22nd-Century-Group-Inc-.png?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="1" height="1" original-src="https://imageproxy.pbkrs.com/https://ml.globenewswire.com/media/MTRiOTZjNmQtOGEwMS00MzU1LWI1ODQtNmMxNDIxOTk5YjlmLTUwMDEzMTQ4NC0yMDI1LTEyLTA5LWVu/tiny/22nd-Century-Group-Inc-.png"/></article></div>

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22nd Century Group, Inc. will participate in the Emerging Growth Virtual Investor Conference on December 10, 2025. CEO Larry Firestone will present at 3:55 PM ET. The company focuses on tobacco harm reduction with its VLN® cigarettes, which contain 95% less nicotine. Investors can register online and submit questions in advance. An archived webcast will be available on the company's Investor Relations website.

22nd Century to Participate in the Emerging Growth Conference on December 10, 2025 | XXII Stock News