
Akeso Reports 80% Response Rate for Ivonescimab Plus Chemotherapy in First-Line TNBC Trial

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Akeso Inc. reported an 80% objective response rate for ivonescimab plus chemotherapy in a Phase II trial for TNBC. The trial showed a 100% disease control rate and a median progression-free survival of 15.2 months. The safety profile was favorable, with no treatment-related discontinuations or deaths. A Phase III trial is ongoing. Results were presented at the 2025 ESMO IO Congress in London.
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