<div id="readability-page-1">09:14 AM EST, 12/17/2025 (MT Newswires) -- Health care stocks were advancing premarket Wednesday, with the State Street Health Care Select Sector SPDR ETF ( XLV ) 0.1% higher and the iShares Biotechnology ETF (IBB) up 0.7%.GSK (GSK) shares were up more than 1% after the company said the US Food and Drug Administration approved Exdensur or depemokimab as an additional maintenance treatment for severe asthma with an eosinophilic phenotype in patients aged 12 years and up.Sagimet Biosciences ( SGMT ) stock was up more than 3% after the company said it has signed a license agreement with Assia Chemical Industries, operating as TAPI Technology &amp; API Services, a subsidiary of Teva Pharmaceutical Industries ( TEVA ) .Compugen ( CGEN ) shares were up more than 13% after the company said it has amended its exclusive license agreement with AstraZeneca ( AZN ) to monetize a portion of its rilvegostomig future royalties. MT Newswires does not provide investment advice. Unauthorized reproduction is strictly prohibited.</div>

SGMT

Health care stocks are advancing premarket Wednesday, with the State Street Health Care Select Sector SPDR ETF up 0.1% and the iShares Biotechnology ETF up 0.7%. GSK shares rose over 1% following FDA approval for a new asthma treatment. Sagimet Biosciences' stock increased by more than 3% after a licensing agreement with TAPI Technology. Compugen shares surged over 13% after amending a license agreement with AstraZeneca.

Sector Update: Health Care Stocks Advance Premarket Wednesday