Key facts: Sanofi's Efdoralprin Alfa gains orphan status; $7.5M to Cytokinetics; rejects most-favored-nation pricing

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2025.12.18 02:03
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Sanofi's Efdoralprin Alfa gained orphan status from the EMA for treating emphysema linked to Alpha-1 Antitrypsin Deficiency, meeting all Phase 2 study endpoints. Data will be presented soon.1Sanofi will pay $7.5 million to Cytokinetics following the approval of Myqorzo for obstructive hypertrophic cardiomyopathy in China, where Sanofi holds exclusive rights.2Sanofi has not accepted the most-favored-nation pricing for drugs, aligning with eleven other pharma firms, while Pfizer, Eli Lilly, AstraZeneca, Novo Nordisk, and EMD Serono have agreed.3