
Gain Therapeutics Reports First Reduction of GluSph in Parkinson’s Patients with GT-02287 in Phase 1b Trial

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Gain Therapeutics Inc. announced positive Phase 1b trial results for GT-02287 in Parkinson’s patients, showing a reduction in glucosylsphingosine (GluSph) in cerebrospinal fluid, indicating increased GCase activity in the brain. This marks the first observed reduction of GluSph following GCase modulator administration in Parkinson’s patients. Results will be discussed in a virtual event on January 6, 2026. The news was originally published by Gain Therapeutics via GlobeNewswire.
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