NASDAQ Composite Index has rose 1.38%, with a year-to-date rose 19.1%; S&amp;P 500 has rose 0.79%, with a year-to-date rose 15.2%; Dow Jones Industrial Average has rose 0.14%, with a year-to-date rose 12.7%.Inspire Medical(INSP) fell 19.45%, with a trading turnover 620.3 Million USD, and a year-to-date fell 48.6%.
Insmed(INSM) fell 16.08%, with a trading turnover 2.2 Billion USD, and a year-to-date rose 141.2%.
Canopy Growth(CGC) fell 11.98%, with a trading turnover 450.3 Million USD, and a year-to-date fell 38.3%.<img src="https://pub.pbkrs.com/screenshot/us_decrease_top_ten_2025-12-19_en-1766095241114953616.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_decrease_top_ten_2025-12-19_en-1766095241114953616.png"/>

INSP

INSM

BIRK

FRMI

EPAC

RZLV

STAA

Inspire Medical(INSP) fell 19.45%, with a trading turnover 620.3 Million USD, and a year-to-date fell 48.6%. Insmed(INSM) fell 16.08%, with a trading turnover 2.2 Billion USD, and a year-to-date rose 141.2%. Canopy Growth(CGC) fell 11.98%, with a trading turnover 450.3 Million USD, and a year-to-date fell 38.3%.

Top 10 US Stock Losers (12.18)