Jacobio Pharma Signs Agreement With AstraZeneca On Pan-KRAS Inhibitor JAB-23E73

rttnews
2025.12.21 14:52
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Jacobio Pharma has signed a strategic agreement with AstraZeneca for its Pan-KRAS inhibitor, JAB-23E73. AstraZeneca gains exclusive rights outside China, while both companies will collaborate within China. Jacobio receives $100 million upfront and potential milestone payments up to $1.915 billion. AstraZeneca will handle development and commercialization outside China. JAB-23E73 targets KRAS mutations, currently in Phase I trials. Jacobio plans further KRAS pathway exploration and immuno-oncology programs.