Stock futures down amidst fading Santa rally hopes, Trump's Fed threats. Initial Jobless Claims awaited. Markets outlook: S&P 500 -0.26%, Dow Jones -0.13%, Nasdaq 100 -0.41%. Treasury bond yields: 10-year at 4.12%, two-year at 3.44%. FedWatch projects 82.8% chance of no interest rate change in January. iSpecimen Inc. shares up 36.95% post $5.5M funding.

U.S. stock futures are down on New Year's Eve after a drop on Tuesday, with hopes of a year-end rally fading. President Trump threatened Fed Chair Powell with a lawsuit, raising market jitters. Markets are awaiting the Initial Jobless Claims report before closing for New Year's Day. The 10-year Treasury bond yielded 4.12% and the two-year bond was at 3.44%. Futures show negativity across major indices with Dow Jones down 0.13%, S&P 500 down 0.26%, Nasdaq 100 down 0.41%, and Russell 2000 down 0.42%. ETFs tracking the S&P 500 and Nasdaq 100 are lower in premarket. iSpecimen Inc. (NASDAQ: ISPC) rose by 36.95% pre-market after securing $5.5 million in private placement. Full article on Benzinga.com.