
BridgeBio Oncology Therapeutics, Inc. Announces New Clinical Data for RAS and PI3Kα Programs

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BridgeBio Oncology Therapeutics, Inc. announced positive preliminary safety and antitumor data for its RAS and PI3Kα programs on January 7, 2026. Key highlights include a 65% overall response rate (ORR) for BBO-8520 in NSCLC patients with KRASG12C mutation, promising efficacy and safety when combined with pembrolizumab, and a partial response in pancreatic cancer with BBO-11818. BBO-10203 showed no hyperglycemia, leading to combination studies in CRC and BC. A company webcast is scheduled for January 7, 2026, at 8:30 a.m. ET.
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