
Acumen Pharmaceuticals Showcases Advances in Alzheimer’s Drug Pipeline Targeting Toxic Amyloid Beta Oligomers

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Acumen Pharmaceuticals Inc. has presented advancements in its Alzheimer’s drug pipeline, focusing on Sabirnetug (ACU193), a monoclonal antibody targeting toxic amyloid beta oligomers, with positive Phase 1 results and Phase 2 results expected in late 2026. The company also introduced its Enhanced Brain Delivery (EBD™) program for better blood-brain barrier penetration. Pre-clinical data for EBD-ACU193 and EBD-ACU234 is anticipated in early 2026. As of September 30, 2025, Acumen reported approximately $136 million in cash, with a cash runway into early 2027.
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