Pre-market hot trades in US stocks: Intelligent Bio Solutions pre-market down 13.37%; DirectBooking Tech pre-market up 8.50%

Pre-market Hot Trades in US Stocks Intelligent Bio Solutions is down 13.37% in pre-market trading. Based on recent news, On January 22, RION announced significant progress in its regenerative medicine technology. RION showcased the potential of its platelet-derived regenerative exosome product (PEP) in clinical and preclinical projects, covering multiple areas such as diabetic foot ulcers, osteoarthritis, and musculoskeletal injuries. This news has drawn market attention to the related technology but has also raised concerns among investors about the market competitiveness of Intelligent Bio Solutions, leading to a decline in its stock price. There have been no other significant news recently. The regenerative medicine field is highly competitive, with rapid technological advancements. DirectBooking Tech is up 8.50% in pre-market trading. Based on recent news, On January 21, DirectBooking Tech's financial report showed a shift from a profit of USD 623,600 to a loss of USD 5.12 million, primarily due to weakened construction activity and a surge in general and administrative expenses. This indicates that the company is facing increasing operational and profitability pressures in the local construction market. On January 20, DirectBooking Tech announced a new service for environmentally friendly processing and reuse of construction and demolition materials, aimed at enhancing its market competitiveness and business diversity. On January 19, analysts gave a buy rating on DirectBooking Tech's technical signals, further boosting market confidence. The Hong Kong construction market is facing challenges, with increased demand for environmental services. Top Gainers in Pre-market US Stocks iOthree is up 156.31% in pre-market trading. Based on recent key news: On January 20, iOThree Ltd. released an important announcement via GlobeNewswire, leading to a significant surge in its stock price. The announcement detailed the company's latest advancements in technological innovation and market expansion, attracting strong investor interest and pushing the stock price up 156.31% in pre-market trading. Source: GlobeNewswire On January 19, the market expressed optimism about iOthree's future growth potential, with analysts raising their earnings expectations. Analysts believe the company's strategic layout in emerging markets will significantly enhance its market share, further boosting investor confidence. Source: Zhito Finance On January 18, iOthree announced a strategic cooperation agreement with a large technology company, expected to bring significant synergies. This cooperation agreement is seen as an important milestone for the company's future development, driving the stock price to continue rising. Source: Wall Street Insight The technology sector has recently performed strongly, with noticeable capital inflows. 60 Degrees Pharmaceuticals is up 37.50% in pre-market trading. There has been no significant news recently; trading is active, and capital flows are evident. Considering sector and industry trends, the stock shows significant volatility, and specific reasons need further observation Leiya Electronics rose 35% in pre-market trading. The significant increase in Leiya Electronics' pre-market trading comes amid a lack of important news recently; trading is active, and capital flows are evident. Considering the sector and industry trends, the stock shows notable volatility, and the specific reasons need further observation