NASDAQ Composite Index has rose 0.01%, with a year-to-date fell 2.3%; S&amp;P 500 has fell 0.21%, with a year-to-date fell 0.9%; Dow Jones Industrial Average has fell 0.07%, with a year-to-date fell 0.7%.Vertex Pharma(VRTX) rose 8.31%, with a trading turnover 1.7 Billion USD, and a year-to-date rose 10.1%.
Corning(GLW) rose 5.56%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 55.9%.
AppLovin(APP) fell 7.7%, with a trading turnover 3.2 Billion USD, and a year-to-date fell 29.2%.
ServiceNow(NOW) fell 4.36%, with a trading turnover 2.6 Billion USD, and a year-to-date fell 23.9%.<img src="https://pub.pbkrs.com/screenshot/us_company_top_five_2026-03-11_en-1773180061433479800.png?x-oss-process=style/lg" original-src="https://pub.pbkrs.com/screenshot/us_company_top_five_2026-03-11_en-1773180061433479800.png"/>

VRTX

BABA

SCCO

INTU

PLTR

Vertex Pharma(VRTX) rose 8.31%, with a trading turnover 1.7 Billion USD, and a year-to-date rose 10.1%. Corning(GLW) rose 5.56%, with a trading turnover 2.3 Billion USD, and a year-to-date rose 55.9%. AppLovin(APP) fell 7.7%, with a trading turnover 3.2 Billion USD, and a year-to-date fell 29.2%. ServiceNow(NOW) fell 4.36%, with a trading turnover 2.6 Billion USD, and a year-to-date fell 23.9%.

- The Nasdaq Composite increased by 0.01% but is down 2.3% year-to-date.  
- The S&P 500 dropped 0.21% and has a year-to-date decline of 0.9%, while the Dow Jones fell 0.07% with a 0.7% year-to-date decrease.  
- Notable stock movements include Vertex Pharmaceuticals rising by 8.31%, Corning increasing by 5.56%, and AppLovin and ServiceNow declining by 7.7% and 4.36%, respectively.

Top 5 US Stock Gainers/Losers (>100B) (3.10)