Shares of IDEAYA Biosciences, Inc. (NASDAQ:IDYA) rose sharply in pre-market trading after the company announced Monday’s webcast to disclose topline results from the ongoing Phase 2/3 registrational trial.



IDEAYA Biosciences shares jumped 18% to $36.00 in pre-market trading.



Here are some other stocks moving in pre-market trading.



<h3>Gainers</h3>



<ul>
<li>Virax Biolabs Group Ltd (NASDAQ:VRAX) gained 82.3% to $0.19 in pre-market trading after dipping over 22% on Friday. Virax Biolabs recently announced that its subsidiary, Virax Biolabs, achieved ISO 13485:2016 and ISO 9001:2015 certification for its quality management system.</li>



<li>Real Messenger Corp (NASDAQ:RMSG) gained 56% to $0.73 in pre-market trading after adding 10% on Friday.</li>



<li>Sky Quarry Inc (NASDAQ:SKYQ) rose 44.1% to $18.14 in pre-market trading after jumping 73% on Friday.</li>



<li>JIADE Ltd (NASDAQ:JDZG) jumped 38.2% to $2.10 in pre-market trading after the company announced its financial results for the fiscal year ended Dec. 31, 2025.</li>



<li>AleAnna Inc (NASDAQ:ANNA) rose 37.7% to $6.87 in pre-market trading after dipping 18% on Friday.</li>



<li>TMD Energy Ltd (NYSE:TMDE) rose 27% to $1.65 in pre-market trading after dipping around 11% on Friday.</li>



<li>Splash Beverage Group, Inc (NYSE:SBEV) rose 25.4% to $0.4827 in pre-market trading after gaining 7% on Friday.</li>



<li>Allogene Therapeutics, Inc. (NASDAQ:ALLO) gained 12.7% to $3.0664 in pre-market trading after the company announced Monday’s webcast to review the interim futility analysis from its pivotal, randomized Phase 2 ALPHA3 trial with cemacabtagene ansegedleucel in first-line consolidation large B-cell lymphoma.</li>



<li>Syntec Optics Holdings, Inc. (NASDAQ:OPTX) rose 10.1% to $10.29 in pre-market trading. On March 31, Syntec Optics reported a year-over-year increase in its fourth-quarter financial results.</li>
</ul>



<h3>Losers</h3>



<ul>
<li>Replimune Group Inc (NASDAQ:REPL) fell 57.5% to $2.02 in pre-market trading. The U.S. Food and Drug Administration (FDA) on Friday concluded that Replimmune Biologics License Application (BLA) for vusolimogene oderparepvec in combination with nivolumab does not provide sufficient evidence of effectiveness for treating advanced melanoma.</li>



<li>Erayak Power Solution Group Inc (NASDAQ:RAYA) declined 19.6% to $0.76 in pre-market trading. Erayak Power Solution Group shares jumped 108% on Friday after the company announced Tri-Fuel Inverter Generators.</li>



<li>Children’s Place Inc (NASDAQ:PLCE) fell 16.8% to $3.30 in pre-market trading after the company posted weaker-than-expected results for the fourth quarter, after the closing bell on Friday.</li>



<li>iSpecimen Inc (NASDAQ:ISPC) dipped 15.7% to $0.11 in pre-market trading. iSpecimen recently announced it reduced its domestic shipments transit times.</li>



<li>FitLife Brands Inc (NASDAQ:FTLF) tumbled 15.1% to $8.17 in pre-market trading.</li>



<li>Nexalin Technology Inc (NASDAQ:NXL) shares dipped 13.4% to $0.35 in pre-market trading after gaining 6% on Friday.</li>



<li>CXApp Inc (NASDAQ:CXAI) fell 13.1% to $0.16 in pre-market trading.</li>



<li>Blue Ridge Bankshares Inc (NYSE:BRBS) fell 12.9% to $3.64 in pre-market trading.</li>



<li>Sana Biotechnology Inc (NASDAQ:SANA) fell 10.1% to $2.78 in pre-market trading.</li>



<li>BitFuFu Inc (NASDAQ:FUFU) dipped 8.2% to $1.84 in pre-market trading. BitFuFu announced March 2026 Bitcoin production and operational updates on Friday.</li>
</ul>



Photo via Shutterstock

IDYA

VRAX

IDEAYA Biosciences shares surged 18% in pre-market trading following the announcement of topline results from its ongoing Phase 2/3 trial. Other notable pre-market movers include Virax Biolabs, which gained 82.3%, and Real Messenger Corp, up 56%. Conversely, Replimune Group saw a significant drop of 57.5% after the FDA deemed its treatment ineffective for advanced melanoma. Overall, several stocks experienced notable gains and losses in pre-market trading today.

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Why IDEAYA Biosciences Shares Are Trading Higher By 18%; Here Are 20 Stocks Moving Premarket