<p>April 29 (Reuters) - Wall Street’s main indexes were mixed at the open on Wednesday as investors treaded carefully ahead of several Big Tech earnings reports and a Federal Reserve meeting expected to be the last for Jerome Powell as its Chair.</p>
<p>The Dow Jones Industrial Average  (.DJI)  rose 21.8 points, or 0.04%, at the open to 49,163.78. The S&amp;P 500  (.SPX)  fell 7.2 points, or 0.10%, at the open to 7,131.61​, while the Nasdaq Composite  (.IXIC)  dropped 57.3 points, or 0.23%, to 24,606.527.</p>

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ONEQ

- Wall Street's main indexes showed mixed performance at the open on April 29 as investors remained cautious ahead of key earnings reports and a Federal Reserve meeting.  
- The Dow Jones Industrial Average increased by 21.8 points to 49,163.78, while the S&P 500 and Nasdaq Composite decreased by 7.2 points and 57.3 points, respectively.  
- The upcoming Federal Reserve meeting is anticipated to be the last for Jerome Powell as Chair.

Reuters

Invesco Nasdaq 100 ETF

US STOCKS SNAPSHOT-Wall St mixed at open ahead of Big Tech earnings, Fed meeting