<div id="readability-page-1" class="page"><div> Lead program is a Phase 1-ready EBV vaccine candidate with potential to prevent infectious mononucleosis and the serious long-term conditions associated with EBV infection , /PRNewswire/ -- Vaccine Company, Inc. (Vaccine Company), a privately held pre-clinical-stage biotechnology company developing next-generation vaccines for infectious diseases, today announced entry into a definitive agreement to be acquired by Lilly. <img src="https://imageproxy.pbkrs.com/https://mma.prnewswire.com/media/2987379/Vaccine_Company_Logo.jpg?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" width="400" height="101" original-src="https://imageproxy.pbkrs.com/https://mma.prnewswire.com/media/2987379/Vaccine_Company_Logo.jpg"/> Vaccine Company's proprietary In Vivo Nanoparticle (IVN) technologies are designed to enable the antigen display known to elicit durable immune responses associated with virus-like particle vaccines, while avoiding the manufacturing burden of traditional VLP production. The company is advancing a broad preclinical pipeline spanning multiple viral pathogens; the lead program applies this technology to Epstein-Barr Virus (EBV) with a five-antigen Phase 1-ready candidate. Given the growing evidence linking EBV to multiple sclerosis and several malignancies, a prophylactic vaccine could prevent not only acute infectious mononucleosis but also the long-term neurological and oncological consequences that may follow infection.Under the terms of the agreement, Lilly will acquire Vaccine Company, and Vaccine Company equity holders could receive up to $1.55 billion in cash, inclusive of an upfront payment and subsequent payments payable upon the achievement of specified clinical and commercial milestones.&#34;Our pipeline of programs, coupled with our proprietary In Vivo Nanoparticle (IVN) technologies, have the potential for global impact,&#34; said Susan Silbermann, MBA, MA, Chief Executive Officer of Vaccine Company, &#34;Together with Lilly, we will be positioned to advance our science, move programs through development, and ultimately deliver vaccines to people around the world.&#34; &#34;Epstein-Barr virus is among the most prevalent human viruses in the world, yet we do not yet have a vaccine against it. Vaccine Company has built a platform we believe may be capable of changing that,&#34; said Daniel M. Skovronsky, M.D., Ph.D., Lilly's chief scientific and product officer, and president, Lilly Research Laboratories. &#34;The case for prevention extends well beyond infectious mononucleosis itself — evidence now links EBV to multiple sclerosis and several malignancies and interrupting that chain earlier could meaningfully reduce the long-term burden of these diseases.&#34;The transaction is subject to customary closing conditions, including expiration of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976.Lazard is acting as exclusive financial advisor, and Cooley LLP is acting as legal counsel to Vaccine Company.About Vaccine Company Vaccine Company is a privately held pre-clinical-stage biotechnology company founded to bring next-generation antigen engineering to vaccine science. The company's proprietary In Vivo Nanoparticle (IVN) technologies are designed to combine the strengths of mRNA and virus-like particle approaches to enable durable, multivalent immune responses to challenging viral targets. Vaccine Company is advancing a pipeline of preclinical and IND-enabling programs, led by a vaccine candidate for the prevention of infectious mononucleosis caused by Epstein-Barr virus. The company was founded in 2022 by ARCH Venture Partners. Luma Group joined as co-founding investor, with further backing from Pfizer Ventures, Wellcome Trust, Lilly Ventures, and Global Health Investment Corporation. Contact InformationMorgan Warners, FGS Global Morgan.warners@fgsglobal.com <img width="12" height="12" src="https://imageproxy.pbkrs.com/https://edge.prnewswire.com/c/img/favicon.png/query-c2Q9MjAyNi0wNS0yNiZzbj1EQzY3NDA1?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" original-src="https://imageproxy.pbkrs.com/https://edge.prnewswire.com/c/img/favicon.png/query-c2Q9MjAyNi0wNS0yNiZzbj1EQzY3NDA1"/> View original content to download multimedia:https://www.prnewswire.com/news-releases/vaccine-company-to-be-acquired-by-lilly-to-advance-best-in-class-vaccine-candidates-for-epstein-barr-virus-and-other-infectious-diseases-302781387.htmlSOURCE Vaccine Company</div></div>

Vaccine Company, Inc. has entered into a definitive agreement to be acquired by Lilly for up to $1.55 billion. The acquisition aims to advance a Phase 1-ready vaccine candidate for Epstein-Barr Virus (EBV), which could prevent infectious mononucleosis and related long-term health issues. The deal is subject to customary closing conditions, and both companies believe the collaboration will enhance vaccine development and global health impact.

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Vaccine Company to be acquired by Lilly to advance best-in-class vaccine candidates for Epstein-Barr Virus and other infectious diseases