Upstream Bio (UPB.US) Shareholders - Institutional Holders, Major Shareholders & Insiders | Longbridge

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Shareholder Type

Institutions72.49%
VC/PE firms14.87%
Sovereign wealth funds5.09%
Private companies4.35%
Others3.20%

Major Shareholders

Major Shareholders Latest
Shareholder
FMR LLC	14.90%	8.16M	0.02%	+61.36K	06/30/2026
OrbiMed Advisors LLC	10.40%	5.69M	0.07%	+0	06/30/2026
Norges Bank Investment Management	6.88%	3.77M	1.58%	+885.97K	06/30/2026
BlackRock, Inc.	6.85%	3.75M	0.66%	+382.67K	06/30/2026
Decheng Capital LLC	4.98%	2.72M	0.03%	+0	06/30/2026
Enavate Sciences	4.49%	2.46M	0.03%	+0	06/30/2026
HBM Healthcare Investments AG	4.01%	2.20M	0.03%	+0	09/30/2025
Vanguard Capital Management, LLC	3.86%	2.12M	<0.01%	+18.62K	06/30/2026
Millennium Management LLC	2.09%	1.14M	0.37%	+206.45K	06/30/2026
D. E. Shaw & Co., L.P.	1.89%	1.04M	0.38%	+215.56K	06/30/2026
Qube Research & Technologies Ltd	1.79%	978.50K	0.65%	+359.18K	06/30/2026
JPMorgan Chase & Co.	1.71%	939.16K	1.01%	+554.81K	06/30/2026
Parkman Healthcare Partners LLC	1.71%	935.25K	0.26%	+148.46K	06/30/2026
Geode Capital Management, LLC	1.70%	931.26K	0.05%	-19.36K	06/30/2026
SEB Funds AB	1.60%	878.47K	0.01%	+0	06/30/2026
Woodline Partners LP	1.52%	831.48K	<0.01%	+0	06/30/2026
State Street Investment Management	1.40%	766.32K	0.10%	+60.97K	06/30/2026
Vanguard Portfolio Management, LLC	1.30%	712.67K	0.04%	-15.04K	06/30/2026
Y-Intercept (Hong Kong) Limited	1.27%	693.56K	0.57%	-307.08K	06/30/2026
Bain Capital Life Sciences Investors, LLC	1.10%	600.95K	0.50%	-266.26K	06/30/2026