iamkun
2026.02.05 14:03

$Novo Nordisk AS(NVO.US) 这是 compounded oral semaglutide:Hims 宣称是 Novo 口服 Wegovy pill 的 “copy”,使用相同活性成分 semaglutide(肽类 GLP-1 受体激动剂),但不是 Novo 授权的完整配方。

• Novo 的品牌口服 Wegovy pill 依赖专利保护的 SNAC 技术(sodium N-[8-(2-hydroxybenzoyl) amino] caprylate),这是吸收增强剂,防止 semaglutide 在胃酸中降解,实现口服生物利用率。

• Hims 的版本几乎不可能真正复制 SNAC(Novo 专利壁垒极高)。它很可能只是简化复方(semaglutide 原料粉末 + 基本载体/填充剂),吸收率/稳定性远低于品牌(易氧化、降解、剂量不准)。

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