<div id="readability-page-1"><div><p><span>Henderson Michael Thomas Chief Executive Officer of Apogee Therapeutics Inc [APGE] filed a Form 4 on November 13, 2025 with the Securities and Exchange Commission disclosing the following changes in ownership:</span></p><div><table><tbody><tr><td><span>Date</span></td><td><span>11/13/25</span></td></tr><tr><td><span>Transaction</span></td><td><span>Planned Sale(1)</span></td></tr><tr><td><span>Shares</span></td><td><span>20,000</span></td></tr><tr><td><span>Price</span></td><td><span>$63.01</span></td></tr><tr><td><span>Value</span></td><td><span>$1,260,236</span></td></tr></tbody></table></div><p><span>Ending Holdings: 1,272,987 - Direct</span></p><ul><li><span>(1)</span></li><li><span>Executed pursuant to a prearranged trading plan (10b5-1).</span></li></ul><p><span>For a free trial, or to learn more about our insider trading analysis and data services, please visit http://www.washingtonservice.com or contact us at (301) 913-5100 or send an email to info@washingtonservice.com.</span></p><p><span>Founded in 1970, The Washington Service provides securities professionals with financial, economic and public policy research and data.</span></p><span> </span></div></div>

APOG

<p>CEO Henderson of Apogee Therapeutics Inc sold 20,000 shares worth $1.3M, as disclosed in a Form 4 filed with the SEC on November 13, 2025. The sale was executed under a prearranged trading plan (10b5-1). Henderson's ending holdings are 1,272,987 shares.</p>

CEO Henderson Sells 20,000 ($1.3M) Of Apogee Therapeutics Inc [APGE]