Burning Rock Reports Third Quarter 2025 Financial Results | BNR Stock News

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2025.11.20 06:52
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Burning Rock Biotech Limited reported its Q3 2025 financial results, showing a 2.3% revenue increase to RMB131.6 million. In-hospital and central lab revenues decreased, while pharma R&D services rose by 68.6%. Gross profit increased by 7.6% to RMB98.8 million, with a gross margin of 75.1%. Operating expenses decreased by 11.9%, driven by budget control and headcount reduction. R&D expenses fell by 15.6%, and selling expenses decreased by 13.6%.

GUANGZHOU, China, Nov. 20, 2025 (GLOBE NEWSWIRE) -- Burning Rock Biotech Limited (NASDAQ: BNR, the “Company” or “Burning Rock”), a company focused on the application of next generation sequencing (NGS) technology in the field of precision oncology, today reported financial results for the three months ended September 30, 2025.

Recent Business Updates

  • Therapy Selection
    • Presented study results at the Cell Reports Medicine on esophageal squamous cell carcinoma in September 2025. “Integrating ctDNA with clinical response evaluation improves residual disease detection post-neoadjuvant chemoradiotherapy to support organsparing strategies and that postoperative ctDNA stratifies recurrence risk beyond pathological response to inform adjuvant immunotherapy decisions”.
  • Early Detection
    • PROMISE study test results presented at The Innovation in September 2025. “The PROMISE study was conducted to investigate the feasibility of a multi-omics integration strategy in multi-cancer detection blood tests across nine types of cancers in head and neck (excluding nasopharynx), esophagus, lung, stomach, liver, biliary tract, pancreas, colorectum, and ovary……Compared to the methylation-based classifier, the multimodal classifier combining methylation and protein features, exhibited an improved sensitivity of 75.1% (95% 75 confidence interval [CI], 69.3%–80.3%) at the same specificity of 98.8% with the accuracy of top predicted origin (TPO1) of 73.1% (95% CI, 66.2%–79.2%)”.
  • Pharma Services
    • The OncoGuide™ OncoScreen™ Plus CDx System based on OncoScreen™ Plus to be used as a companion diagnostic for AstraZeneca’s capivasertib has received Manufacturing and Marketing Approval from Japan’s Ministry of Health, Labour and Welfare (MHLW) in September, 2025.

Third Quarter 2025 Financial Results

Total revenues were RMB131.6 million (US$18.5 million) for the three months ended September 30, 2025, representing a 2.3% increase from RMB128.6 million for the same period in 2024.

  • Revenue generated from in-hospital business was RMB52.8 million (US$7.4 million) for the three months ended September 30, 2025, representing a 17.1% decrease from RMB63.8 million for the same period in 2024, driven by a decrease in sales volume.
  • Revenue generated from central laboratory business was RMB36.8 million (US$5.2 million) for the three months ended September 30, 2025, representing a 7.9% decrease from RMB40.0 million for the same period in 2024, primarily attributable to a decrease in the number of tests, as we continued our transition towards in-hospital testing.
  • Revenue generated from pharma research and development services was RMB42.0 million (US$5.9 million) for the three months ended September 30, 2025, representing a 68.6% increase from RMB24.9 million for the same period in 2024, primarily attributable to an increased development and testing services performed for our pharma customers.

Cost of revenues was RMB32.8 million (US$4.6 million) for the three months ended September 30, 2025, representing an 10.9% decrease from RMB36.8 million for the same period in 2024.

Gross profit was RMB98.8 million (US$13.9 million) for the three months ended September 30, 2025, representing a 7.6% increase from RMB91.8 million for the same period in 2024. Gross margin was 75.1% for the three months ended September 30, 2025, compared to 71.4% for the same period in 2024. By channel, gross margin of central laboratory business and in-hospital business were 81.8% and 71.8% for the three months ended September 30, 2025, compared to 83.2% and 73.0% during the same period in 2024, primarily due to the cost reduction caused by the rent subsidy for the headquarter building in the third quarter of 2024; gross margin of pharma research and development services was 73.4% for the three months ended September 30, 2025, compared to 48.2% during the same period of 2024, primarily due to the significant increase in revenue from high-margin companion diagnostic (CDx) projects.

Non-GAAP gross profit, which excludes depreciation and amortization expenses, was RMB100.9 million (US$14.2million) for the three months ended September 30, 2025, representing a 3.2% increase from RMB97.8 million for the same period in 2024. Non-GAAP gross margin was 76.7% for the three months ended September 30, 2025, compared to 76.0% for the same period in 2024.

Operating expenses were RMB115.0 million (US$16.2 million) for the three months ended September 30, 2025, representing a 11.9% decrease from RMB130.4 million for the same period in 2024. The decrease was primarily driven by decreases in amortized expense on share-based compensation, budget control measures and headcount reduction to improve the Company’s operating efficiency.

  • Research and development expenses were RMB41.5 million (US$5.8 million) for the three months ended September 30, 2025, representing a 15.6% decrease from RMB49.2 million for the same period in 2024, primarily due to (i) a decrease in the expenditure for research projects; (iii) a decrease in amortized expense on share-based compensation; and (iv) a decrease in amortized expenses for office building decoration.
  • Selling and marketing expenses were RMB41.8 million (US$5.9 million) for the three months ended September 30, 2025, representing a 13.6% decrease from RMB48.4 million for the same period in 2024, primarily due to (i) a decrease in staff cost resulted from the reorganization of the sales department and improvement in operating efficiency; (ii) a decrease in amortized expense on share-based compensation; and (iii) a decrease in amortized expenses for office building decoration.
  • General and administrative expenses were RMB31.7 million (US$4.5 million) for the three months ended September 30, 2025, representing a 3.6% decrease from RMB32.9 million for the same period in 2024, primarily due to (i) a decrease in the general and administrative personnel’s staff cost; (ii) a decrease in amortized expense on share-based compensation; and partially offset by (i) an increase in impairment expenses for accounts receivables and contract assets; (iii) an increase in operating lease.

Net loss was RMB16.8 million (US$2.4 million) for the three months ended September 30, 2025, compared to RMB35.7 million for the same period in 2024.

Cash, cash equivalents and restricted cash were RMB467.0 million (US$65.6 million) as of September 30, 2025.

About Burning Rock

Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.

For more information about Burning Rock, please visit: ir.brbiotech.com.

Safe Harbor Statement

This press release contains forward-looking statements. These statements constitute “forward-looking” statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates,” “target,” “confident” and similar statements. Burning Rock may also make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Burning Rock’s beliefs and expectations, are forward-looking statements. Such statements are based upon management’s current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond Burning Rock’s control. Forward-looking statements involve risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. All information provided in this press release is as of the date of this press release, and Burning Rock does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.

Non-GAAP Measures

In evaluating the business, the Company considers and uses non-GAAP measures, such as non-GAAP gross profit and non-GAAP gross margin, as supplemental measures to review and assess operating performance. The presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”). The company defines non-GAAP gross profit as gross profit excluding depreciation and amortization. The company defines non-GAAP gross margin as gross margin excluding depreciation and amortization.

The company presents these non-GAAP financial measures because they are used by management to evaluate operating performance and formulate business plans. The company believe non-GAAP gross profit and non-GAAP gross margin excluding non-cash impact of depreciation and amortization reflect the company’s ongoing business operations in a manner that allows more meaningful period-to-period comparisons.

Contact: IR@brbiotech.com

Selected Operating Data
As of
September 30,
2024
December 31,
2024
March 31,
2025
June 30,
2025
September 30,
2025
In-hospital Channel:
Pipeline partner hospitals(1)3029303031
Contracted partner hospitals(2)6163636363
Total number of partnerhospitals6992939394
(1)Refers to hospitals that are in the process of establishing in-hospital laboratories, laboratory equipment procurement or installation, staff training or pilot testing using the Company’s products.
(2)Refers to hospitals that have entered into contracts to purchase the Company’s products for use on a recurring basis in their respective in-hospital laboratories the Company helped them establish. Kit revenue is generated from contracted hospitals.
Selected Financial Data
For the three months ended
For the nine months ended
RevenuesSeptember 30,
2024
September 30,
2025
September 30,
2024
September 30,
2025
(RMB in thousands)
(RMB in thousands)
Central laboratory channel39,98436,811136,371115,968
In-hospital channel63,76952,847181,028173,030
Pharma research and development channel24,89141,95972,401124,255
Total revenues128,644131,617389,800413,253
For the three months ended
For the nine months ended
Revenues by location of customerSeptember 30,
2024
September 30,
2025
September 30,
2024
September 30,
2025
(RMB in thousands)
(RMB in thousands)
Overseas25,84017,21459,55379,079
Mainland China102,804114,403330,247334,174
Total Revenues128,644131,617389,800413,253
For the three months ended
For the nine months ended
Gross profitSeptember 30,
2024
September 30, 2025September 30,
2024
September 30, 2025
(RMB in thousands)
(RMB in thousands)
Central laboratory channel33,26230,126108,68898,254
In-hospital channel46,58037,925129,830128,310
Pharma research and development channel12,00430,79334,46077,784
Total gross profit91,84698,844272,978304,348
For the three months ended
For the nine months ended
Share-based compensation expensesSeptember 30,
2024
September 30,
2025
September 30,
2024
September 30,
2025
(RMB in thousands)
(RMB in thousands)
Cost of revenues2893011,349889
Research and development expenses3,1807327,4751,603
Selling and marketing expenses1,9176243,6572,013
General and administrative expenses4,7322,831115,1296,249
Total share-based compensation expenses10,1183,829147,61010,754
Burning Rock Biotech Limited
Unaudited Condensed Statements of Comprehensive Loss
(in thousands, except for number of shares and per share data)
For the three months ended
September 30,
2024
December 31,
2024
March 31,
2025
June 30,
2025
September 30,
2025
September 30,
2025
RMBRMBRMBRMBRMBUS$
Revenues128,644126,022133,082148,554131,61718,488
Cost of revenues(36,798)(36,600)(35,681)(40,451)(32,773)(4,604)
Gross profit91,84689,42297,401108,10398,84413,884
Operating expenses:
Research and development expenses(49,150)(52,203)(40,389)(49,770)(41,469)(5,825)
Selling and marketing expenses(48,411)(46,730)(40,888)(38,413)(41,808)(5,873)
General and administrative expenses(32,874)(37,289)(31,303)(31,417)(31,698)(4,453)
Impairment loss on long-lived assets-(35,127)----
Total operating expenses(130,435)(171,349)(112,580)(119,600)(114,975)(16,151)
Loss from operations(38,589)(81,927)(15,179)(11,497)(16,131)(2,267)
Interest income3,1731,8142,5812,2261,744245
Interest expense----(15)(2)
Other income (expense), net14,353(652)38771
Foreign exchange loss, net(129)(220)(26)(574)(2,151)(302)
Loss before income tax(35,544)(75,980)(13,276)(9,458)(16,546)(2,325)
Income tax expenses(201)(5,314)(224)(244)(212)(30)
Net loss(35,745)(81,294)(13,500)(9,702)(16,758)(2,355)
Net loss attributable to Burning Rock Biotech Limited’s shareholders(35,745)(81,294)(13,500)(9,702)(16,758)(2,355)
Net loss attributable to ordinary shareholders(35,745)(81,294)(13,500)(9,702)(16,758)(2,355)
Loss per share for class A and class B ordinary shares:
Class A ordinary shares - basic and diluted(0.35)(0.79)(0.13)(0.09)(0.16)(0.02)
Class B ordinary shares - basic and diluted(0.35)(0.79)(0.13)(0.09)(0.16)(0.02)
Weighted average shares outstanding used in loss per share computation:
Class A ordinary shares - basic and diluted85,902,67086,036,28690,291,65890,357,97090,416,61990,416,619
Class B ordinary shares - basic and diluted17,324,84817,324,84817,324,84817,324,84817,324,84817,324,848
Other comprehensive (loss) income, net of tax of nil:
Foreign currency translation adjustments(4,054)6,009(72)(243)(1,724)(242)
Total comprehensive loss(39,799)(75,285)(13,572)(9,945)(18,482)(2,597)
Total comprehensive loss attributable to Burning Rock Biotech Limited’s shareholders(39,799)(75,285)(13,572)(9,945)(18,482)(2,597)
Burning Rock Biotech Limited
Unaudited Condensed Statements of Comprehensive Loss
(in thousands, except for number of shares and per share data)
For the nine months ended
September 30,
2024
September 30,
2025
September 30,
2025
RMBRMBUS$
Revenues389,800413,25358,049
Cost of revenues(116,822)(108,905)(15,299)
Gross profit272,978304,34842,750
Operating expenses:
Research and development expenses(180,087)(131,628)(18,490)
Selling and marketing expenses(144,174)(121,109)(17,012)
General and administrative expenses(224,349)(94,418)(13,263)
Total operating expenses(548,610)(347,155)(48,765)
Loss from operations(275,632)(42,807)(6,015)
Interest income10,3986,551920
Interest expense-(15)(2)
Other income, net353(258)(36)
Foreign exchange gain (loss), net120(2,751)(386)
Loss before income tax(264,761)(39,280)(5,519)
Income tax expenses(571)(680)(96)
Net loss(265,332)(39,960)(5,615)
Net loss attributable to Burning Rock Biotech Limited’s shareholders(265,332)(39,960)(5,615)
Net loss attributable to ordinary shareholders(265,332)(39,960)(5,615)
Loss per share for class A and class B ordinary shares:
Class A ordinary shares - basic and diluted(2.58)(0.37)(0.05)
Class B ordinary shares - basic and diluted(2.58)(0.37)(0.05)
Weighted average shares outstanding used in loss per share computation:
Class A ordinary shares - basic and diluted85,467,13190,332,67290,332,672
Class B ordinary shares - basic and diluted17,324,84817,324,84817,324,848
Other comprehensive loss, net of tax of nil:
Foreign currency translation adjustments(2,524)(2,039)(286)
Total comprehensive loss(267,856)(41,999)(5,901)
Total comprehensive loss attributable to Burning Rock Biotech Limited’s shareholders(267,856)(41,999)(5,901)
Burning Rock Biotech Limited

Unaudited Condensed Consolidated Balance Sheets

(In thousands)

As of
December 31,
2024
September 30,
2025
September 30,
2025
RMBRMBUS$
ASSETS
Current assets:
Cash and cash equivalents519,849463,99465,177
Restricted cash2,3132,985419
Accounts receivable, net152,013183,84125,824
Contract assets, net13,85513,0491,833
Inventories, net62,62554,4697,651
Prepayments and other current assets, net25,96320,9852,950
Total current assets776,618739,323103,854

Non-current assets:
Property and equipment, net47,15233,7554,742
Operating right-of-use assets53,18832,2814,534
Intangible assets, net42131644
Other non-current assets7,9266,493912
Total non-current assets108,68772,84510,232
TOTAL ASSETS885,305812,168114,086
Burning Rock Biotech Limited

Unaudited Condensed Consolidated Balance Sheets (Continued)

(in thousands)

As of
December 31,
2024
September 30,
2025
September 30,
2025
RMBRMBUS$
LIABILITIES AND SHAREHOLDERS’ EQUITY
Current liabilities:
Accounts payable33,74734,2774,815
Deferred revenue117,895106,44814,953
Accrued liabilities and other current liabilities89,49876,99210,816
Customer deposits59259283
Short-term borrowings-20028
Current portion of operating lease liabilities24,56716,6032,332
Total current liabilities266,299235,11233,027
Non-current liabilities:
Long-term borrowings-1,800253
Non-current portion of operating lease liabilities27,75414,5772,048
Other non-current liabilities10,42511,1021,559
Total non-current liabilities38,17927,4793,860
TOTAL LIABILITIES304,478262,59136,887

Shareholders’ equity:
Class A ordinary shares12412017
Class B ordinary shares21213
Additional paid-in capital5,002,2555,006,937703,320
Treasury stock(63,264)(57,193)(8,034)
Accumulated deficits(4,200,261)(4,240,221)(595,620)
Accumulated other comprehensive loss(158,048)(160,087)(22,487)
Total shareholders’ equity580,827549,57777,199
TOTAL LIABILITIES AND SHAREHOLDERS’ EQUITY885,305812,168114,086
Burning Rock Biotech Limited

Unaudited Condensed Statements of Cash Flows

(in thousands)

For the three months ended
September
30,2024
September
30,2025
September 30,
2025
RMBRMBUS$
Net cash used in operating activities(30,278)16,3942,303
Net cash used in investing activities(987)(2,747)(386)
Net cash generated from financing activities2--
Effect of exchange rate on cash, cash equivalents and restricted cash(3,537)(1,692)(237)
Net decrease in cash, cash equivalents and restricted cash(34,800)11,9551,680
Cash, cash equivalents and restricted cash at the beginning of period533,047455,02463,916
Cash, cash equivalents and restricted cash at the end of period498,247466,97965,596
For the nine months ended
September
30,2024
September
30,2025
September
30,2025
RMBRMBUS$
Net cash used in operating activities(111,323)(51,482)(7,232)
Net cash used in investing activities(3,600)(4,071)(572)
Net cash generated from financing activities22,000281
Effect of exchange rate on cash, cash equivalents and restricted cash(2,048)(1,630)(229)
Net decrease in cash, cash equivalents and restricted cash(116,969)(55,183)(7,752)
Cash, cash equivalents and restricted cash at the beginning of period615,216522,16273,348
Cash, cash equivalents and restricted cash at the end of period498,247466,97965,596
Burning Rock Biotech Limited

Reconciliations of GAAP and Non-GAAP Results

For the three months ended
September 30,
2024
December 31,
2024
March 31,
2025
June 30,
2025
September 30,
2025
(RMB in thousands)
Gross profit:
Central laboratory channel33,26233,15332,19135,93730,126
In-hospital channel46,58029,56343,89546,49037,925
Pharma research and development channel12,00426,70621,31525,67630,793
Total gross profit
91,84689,42297,401108,10398,844
Add: depreciation and amortization:
Central laboratory channel1,2771,010562456231
In-hospital channel798623290389372
Pharma research and development channel3,8462,5342,4121,5281,491
Total depreciation and amortization included in cost of revenues
5,9214,1673,2642,3732,094
Non-GAAP gross profit:
Central laboratory channel34,53934,16332,75336,39330,357
In-hospital channel47,37830,18644,18546,87938,297
Pharma research and development channel15,85029,24023,72727,20432,284
Total non-GAAP gross profit97,76793,589100,665110,476100,938
Non-GAAP gross margin:
Central laboratory channel86.4%87.0%85.5%89.1%82.5%
In-hospital channel74.3%69.5%76.6%75.0%72.5%
Pharma research and development channel63.7%67.6%64.0%60.2%76.9%
Total non-GAAP gross margin76.0%74.3%75.6%74.4%76.7%