Buy Rating on Structure Therapeutics, Inc. Driven by Aleniglipron’s Potential in the Obesity Market

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2025.11.20 12:55
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Evan Seigerman from BMO Capital reiterated a Buy rating on Structure Therapeutics, Inc. with a $100 price target, driven by the potential of its oral GLP-1 receptor agonist, aleniglipron, in the obesity market. The ACCESS trials are expected to show significant weight loss efficacy. Despite short-term pricing pressures, the long-term growth potential remains strong. Cantor Fitzgerald also maintained a Buy rating with a $65 target.

In a report released today, Evan Seigerman from BMO Capital reiterated a Buy rating on Structure Therapeutics, Inc. Sponsored ADR, with a price target of $100.00.

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Evan Seigerman has given his Buy rating due to a combination of factors that highlight the potential of Structure Therapeutics, Inc.’s oral GLP-1 receptor agonist, aleniglipron, in the obesity market. The upcoming results from the ACCESS and ACCESS II trials are anticipated to demonstrate significant weight loss efficacy, particularly with the 120mg dosage, which is expected to be competitive with existing treatments like orforglipron.
The scarcity of effective oral small molecule GLP-1 receptor agonists and the use of the Chugai scaffold, which has been validated by orforglipron, add value to aleniglipron. Despite being behind competitors in the timeline, the early-stage nature of the oral GLP-1 obesity market presents a substantial opportunity for growth. Additionally, while there are short-term pricing pressures due to U.S. government agreements, the long-term growth potential remains strong, supporting the Outperform rating and a target price of $100 per share.

In another report released on November 13, Cantor Fitzgerald also maintained a Buy rating on the stock with a $65.00 price target.