Personalis NeXT Personal Test Shows High Sensitivity for Lung Cancer MRD Detection in Landmark Study

Reuters
2025.12.11 14:00
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Personalis, Inc. announced results from a clinical study using its NeXT Personal® test for detecting molecular residual disease in non-small cell lung cancer. The study, published in Cell, analyzed 431 patients over five years, showing high sensitivity in detecting circulating tumor DNA. Key findings include detection of residual and recurrent cancer at multiple stages, with 36-43% in the ultrasensitive range. Patients not clearing ctDNA during chemotherapy were more likely to relapse. Results were published in Cell.