Insmed Discontinues Brensocatib CRSsNP Program After Phase 2b Trial Misses Endpoints

Reuters
2025.12.17 21:01
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Insmed Inc. has discontinued its brensocatib CRSsNP program after the Phase 2b trial failed to meet efficacy endpoints. The drug was well tolerated with no new safety signals. Insmed plans to present the study data at a future congress and has acquired INS1148, a Phase 2 ready monoclonal antibody for respiratory and inflammatory diseases, advancing it into Phase 2 development for interstitial lung disease and asthma.