Novo files marketing application for next-gen weight-loss drug

Reuters
2025.12.18 13:14
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Dec 18 (Reuters) - Novo Nordisk (NOVOb.CO) said on Thursday it had filed a marketing application with the U.S. Food and Drug Administration for CagriSema, its once-weekly next-generation weight-loss drug.The regulator is expected to review the application in 2026, Novo said.The Danish drugmaker had positioned CagriSema as a more potent successor to its blockbuster drug, Wegovy, but lower-than-expected weight loss in two prior studies disappointed investors.The drug combines cagrilintide, which mimics pancreatic hormone amylin, and semaglutide, the active ingredient in Novo’s blockbuster weight-loss drug Wegovy.