Sanofi’s Efdoralprin Alfa Shows Superiority in Phase 2 Study for Alpha-1 Antitrypsin Deficiency Emphysema

Reuters
2025.12.23 14:53
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Sanofi's efdoralprin alfa has received orphan designation from the EMA for treating AATD-related emphysema. The drug showed superiority in a Phase 2 study, meeting all primary and key secondary endpoints compared to standard plasma-derived therapy. Results will be presented at an upcoming medical meeting. The drug is still in clinical development, with safety and efficacy not yet evaluated by regulatory authorities.