<div id="readability-page-1">US stock futures are slightly lower this Wednesday morning, but several individual stocks are making sharp moves on index changes, FDA approvals, earnings, and corporate actions. Here are the stocks investors are watching today: UiPath (PATH) Surged after S&amp;P Dow Jones Indices announced UiPath will join the S&amp;P MidCap 400, replacing Synovus Financial, effective January 2, 2026. Shares jumped 6.8 percent to $17.05 in after-hours trading. Agios Pharmaceuticals (AGIO) Announced FDA approval of Mitapivat (EcVSmi) to treat anemia in adults with alpha or beta thalassemia. Despite the approval, shares slipped 1.4 percent to $24.59. Fight BioPharma (FIGHT) Announced a 1-for-3000 reverse stock split, sending shares down 28.8 percent to $0.17 after hours. Cush Pharmaceuticals (CUSH) Delivered better-than-expected Q4 results, posting a $0.11 loss per share versus estimates of a $0.43 loss. Shares surged 22.1 percent to $1.27 after hours. Ramaco Resources (METC) Jumped 7.1 percent to $18.09 after announcing a $100 million share buyback program.</div>

AGIO

METC

PATH

<p>US stock futures are slightly lower, but individual stocks are making sharp moves. UiPath surged 6.8% after joining the S&P MidCap 400. Agios Pharmaceuticals slipped 1.4% despite FDA approval of Mitapivat. Fight BioPharma fell 28.8% after a reverse stock split. Cush Pharmaceuticals surged 22.1% on better-than-expected Q4 results. Ramaco Resources jumped 7.1% after announcing a $100 million share buyback program.</p>

Top 5 stocks to watch today | Stock market is open Christmas Eve