FDA approved Novo Nordisk A/S' Wegovy pill (25mg oral semaglutide) for weight loss. 16.6% mean weight loss in trial.

Unusual Whales
2025.12.26 19:58
The FDA recently approved Novo Nordisk A/S' Wegovy pill, containing 25 mg of oral semaglutide, as a weight management treatment. This marks the first approval of an oral glucagon-like peptide-1 (GLP-1) receptor agonist for weight management. Clinical trials such as OASIS 4 showed that the pill led to a 16.6% mean weight loss in adults with obesity or overweight with comorbidities. The pill's efficacy was comparable to the injectable version of Wegovy at 2.4 mg, with one in three participants experiencing a 20% or greater weight reduction. Novo Nordisk plans to launch the Wegovy pill soon.