<div id="readability-page-1">Major market indexes on Wall Street ended higher on Friday as the highly anticipated debut of SpaceX grabbed investors' attention. Wall Street had a slew of upgrades and downgrades from analysts. Here are some of the major calls for the week: Pfizer upgraded by RBC on risk-reward setup RBC upgraded Pfizer (PFE) to Sector Perform from Underperform, ...</div>

ILMN

INTC

<p>Wall Street analysts issued notable upgrades and downgrades this week. Pfizer, Intel, AMD, Illumina, and chip equipment makers received upgrades citing balanced risk-reward, AI potential, and strong spending. Conversely, Nike was downgraded due to a slower-than-expected turnaround. Despite its historic IPO, SpaceX received its first Sell rating from CFRA due to concerns over unproven commercial outcomes.</p>

- Major market indexes on Wall Street closed higher, driven by the debut of SpaceX.  
- Analysts made several upgrades and downgrades, notably upgrading Pfizer from Underperform to Sector Perform.  
- This shift in analyst ratings reflects changing risk-reward dynamics in the market.

Pfizer

Illumina

Intel

Space Exploration Tech

Nike

INTEL-T

Direxion Daily AMD Bull 2X Shares

GraniteShares 2x Long INTC Daily ETF

Direxion Daily AMD Bear 1X Shares

GraniteShares 2x Long AMD Daily ETF

2倍做多SpaceX ETF-leverage shares

ProShares Ultra SpaceX ETF

GraniteShares 2x Long SpaceX Daily ETF

GraniteShares 2x Short SpaceX Daily ETF

Leverage Shares 2x Short SPCX Daily ETF

Defiance Daily Target 2X Long SpaceX ETF

ROYAL BANK OF CANADA

Notable analyst calls this week: Pfizer, AMD and Intel among top picks