Upstream Bio

UPB

6.5201.72% ( +0.110 )

Trading: Jul 30, 14:18:14 (EDT)

UPB

6.5201.72% ( +0.110 )

Trading: Jul 30, 14:18:14 (EDT)

Major Shareholders Latest
Shareholder
FMR LLC	14.89%	8.10M	1.03%	+583.36K	03/31/2026
OrbiMed Advisors LLC	10.46%	5.69M	0.04%	+0	03/31/2026
BlackRock, Inc.	6.19%	3.37M	0.03%	+26.19K	03/31/2026
Norges Bank Investment Management	5.30%	2.88M	0.02%	+0	12/31/2025
Decheng Capital LLC	5.01%	2.72M	0.79%	-418.21K	03/31/2026
Enavate Sciences	4.52%	2.46M	0.02%	+0	03/31/2026
HBM Healthcare Investments AG	4.03%	2.20M	0.01%	+0	09/30/2025
Vanguard Capital Management, LLC	3.44%	1.87M	--	+1.87M	03/31/2026
Federated Hermes, Inc.	1.80%	979.76K	1.80%	+979.28K	03/31/2026
Geode Capital Management, LLC	1.75%	950.62K	0.18%	+98.71K	03/31/2026
Millennium Management LLC	1.72%	937.32K	0.77%	+420.06K	03/31/2026
SEB Funds AB	1.61%	878.47K	--	+878.47K	03/31/2026
Bain Capital Life Sciences Investors, LLC	1.59%	867.21K	0.86%	-462.33K	03/31/2026
Woodline Partners LP	1.53%	831.48K	0.13%	+71.23K	03/31/2026
D. E. Shaw & Co., L.P.	1.51%	820.48K	1.46%	+793.39K	03/31/2026
Parkman Healthcare Partners LLC	1.45%	786.78K	0.09%	-47.78K	03/31/2026
Samsara BioCapital LLC	1.35%	736.05K	<0.01%	+0	03/31/2026
Pictet Asset Management Limited	1.35%	733.43K	0.08%	-39.72K	03/31/2026
Vanguard Portfolio Management, LLC	1.34%	727.71K	--	+727.71K	03/31/2026
State Street Global Advisors, Inc.	1.30%	705.35K	1.14%	-613.88K	03/31/2026

All Shareholders