<p>一项发表在《医学互联网研究杂志》(JMIR) 上的真实世界证据研究报告了对 3546 名来自德国、奥地利和波兰女性的调查结果，显示出高痛苦负担但低诊断率；针对性的在线活动展示了强大的能力来吸引受影响的、通常未被诊断的人群。</p>
<p>, /PRNewswire/ -- <strong>SubjectWell</strong>，一个推动可预测临床试验招募和患者留存的患者体验平台，宣布在《医学互联网研究杂志》(JMIR) 上发表了一篇经过同行评审的论文，强调了公司在推进临床试验招募科学和改善患者获取方面的承诺，这次聚焦于女性健康，关注月经疼痛和痛经。</p>
<p>“数百万女性承受着显著的月经疼痛，但在医疗系统中却未被关注，” SubjectWell 首席执行官 Fred Martin 表示。“这项工作表明，数字化的以患者为中心的外展可以在患者需要的地方与他们接触，进行大规模倾听，并邀请他们参与研究，最终扩大公平性并加速女性健康领域的证据生成。”</p>
<p>这项真实世界证据研究通过在德国、奥地利和波兰进行针对性的谷歌和 Facebook 外展，考察了经历月经痉挛的女性的诊断模式、痛苦负担和临床试验准备情况。研究结果表明，尽管痛苦水平很高，但痛经的诊断存在很大的差距，并显示直接面向患者的沟通可以吸引在传统医疗环境中常常被忽视的广泛多样的人群。</p>
<p><strong>主要发现包括：</strong></p>
<p><strong>尽管痛苦严重，但诊断差距显著</strong></p>
<p>在报告与痛经一致症状的受访者中，仅有 4.6% 的人报告获得了诊断，尽管 88.5% 的德国和奥地利受影响女性报告的疼痛评分≥6/10，波兰的疼痛水平甚至更高。</p>
<p><strong>数字外展准确找到合适的患者</strong> 针对性的在线活动展示了高特异性，94.6% 的受访者符合痛经的症状标准，支持直接面向患者的策略作为识别未被充分认识患者的有效工具。</p>
<p><strong>为何诊断被遗漏</strong></p>
<p>大约 90.3% 的女性没有寻求医疗建议，或对自己的诊断不确定，或表示她们的症状未被视为病理性。在那些被诊断的患者中，近一半的痛经样症状患者仅被标记为经前综合症 (PMS)，突显了对痛经的潜在低识别率。</p>
<p><strong>PMS 的识别率相对较高</strong></p>
<p>在已诊断的病例中，77.3% 报告为 PMS 诊断，8.6% 的 PMS 症状女性报告被诊断，几乎是同一人群中痛经诊断率的两倍。</p>
<p>这些发现强化了 SubjectWell 以证据为驱动的以患者为中心的招募方法。通过量化覆盖范围和诊断差距，该研究表明，直接面向患者的策略可以扩大对未被诊断或当前未寻求护理的女性的临床试验意识，同时为研究人员提供更全面的真实世界症状负担视角。</p>
<p>“我们旨在了解直接面向患者的沟通如何改善经历月经疼痛者的获取，” SubjectWell 科学事务总监 Matthias Roos 表示。“数据清楚地表明，数字策略可以快速而尊重地与合适的患者建立联系，为更具包容性的女性健康研究奠定基础。”</p>
<p><em>该项目由 Bionorica SE 资助并与其合作进行，旨在评估临床试验患者招募策略，并在出版物中得到了认可。</em></p>
<p>完整文章可在此查看：https://www.jmir.org/2025/1/e68148</p>
<p>有关 SubjectWell 患者招募解决方案的更多信息，请访问 <strong>www.subjectwell.com</strong>。</p>
<p><strong>关于 SubjectWell</strong></p>
<p>作为首屈一指的患者体验平台，SubjectWell 通过增强患者旅程，从方案设计到研究完成，推动可预测的试验入组并改善留存。凭借技术、全球覆盖、全方位创意和一系列减少现场负担的服务，SubjectWell 为赞助商、CRO、现场和现场网络提供智能和效率。从方案开发到招募、入组、留存和试验后的真实世界证据研究，SubjectWell 支持整个临床生命周期。欲了解更多信息，请访问 www.subjectwell.com。</p>
<p><strong>媒体联系人：</strong></p>
<p>Alysha Swisher / Haylee Elmore</p>
<p>Interdependence PR</p>
<p>[email protected]</p>
<p>6023501455</p>
<p>来源 SubjectWell</p>
<p><img src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjUwOTIzJk5ld3NJdGVtSWQ9UEg4MDIyOCZUcmFuc21pc3Npb25fSWQ9MjAyNTA5MjMwODU4UFJfTkVXU19VU1BSX19fX19QSDgwMjI4?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" alt="" original-src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjUwOTIzJk5ld3NJdGVtSWQ9UEg4MDIyOCZUcmFuc21pc3Npb25fSWQ9MjAyNTA5MjMwODU4UFJfTkVXU19VU1BSX19fX19QSDgwMjI4"/></p>

<p>SubjectWell 宣布了一项发表在 JMIR 上的同行评审研究，强调德国、奥地利和波兰女性在痛经诊断方面存在显著差距。尽管疼痛水平很高，但只有 4.6% 的女性报告获得了诊断。该研究强调了直接面向患者的宣传在吸引未诊断人群方面的有效性，显示出 90.3% 的女性没有寻求医疗建议。研究结果表明，数字化策略可以提高临床试验的认知度，并改善经历月经疼痛女性的医疗服务获取</p>

<p><em>A real-world evidence study published in JMIR reports results on a survey of 3,546 women in Germany, Austria, and Poland showing high pain burden but low diagnosis rates; targeted online campaigns demonstrated strong ability to engage affected, often undiagnosed, populations</em></p>
<div class="lb-trans"><p>一项发表在《医学互联网研究杂志》(JMIR) 上的真实世界证据研究报告了对 3546 名来自德国、奥地利和波兰女性的调查结果，显示出高痛苦负担但低诊断率；针对性的在线活动展示了强大的能力来吸引受影响的、通常未被诊断的人群。</p>
</div><p>, /PRNewswire/ -- <strong>SubjectWell</strong>, the patient experience platform driving predictable clinical trial recruitment and patient retention, announced the publication of a peer-reviewed paper in the Journal of Medical Internet Research (JMIR) underscoring the company's commitment to advancing the science of clinical trial recruitment and improving patient access, this time in women's health, focusing on menstrual pain and dysmenorrhea.</p>
<div class="lb-trans"><p>, /PRNewswire/ -- <strong>SubjectWell</strong>，一个推动可预测临床试验招募和患者留存的患者体验平台，宣布在《医学互联网研究杂志》(JMIR) 上发表了一篇经过同行评审的论文，强调了公司在推进临床试验招募科学和改善患者获取方面的承诺，这次聚焦于女性健康，关注月经疼痛和痛经。</p>
</div><p>&#34;Millions of women live with significant menstrual pain but remain unseen by the healthcare system,&#34; said Fred Martin, CEO of SubjectWell. &#34;This work shows that digital, patient-first outreach can meet people where they are, listen at scale, and invite them into research, ultimately expanding equity and accelerating evidence generation in women's health.&#34;</p>
<div class="lb-trans"><p>“数百万女性承受着显著的月经疼痛，但在医疗系统中却未被关注，” SubjectWell 首席执行官 Fred Martin 表示。“这项工作表明，数字化的以患者为中心的外展可以在患者需要的地方与他们接触，进行大规模倾听，并邀请他们参与研究，最终扩大公平性并加速女性健康领域的证据生成。”</p>
</div><p>The real-world evidence study, conducted via targeted Google and Facebook outreach across Germany, Austria, and Poland, examines diagnosis patterns, pain burden, and clinical-trial readiness among women experiencing menstrual cramps. Findings indicate a large diagnostic gap for dysmenorrhea despite substantial pain levels and show that direct-to-patient (DTP) communication can engage broad, diverse populations who are often missed in traditional medical settings.</p>
<div class="lb-trans"><p>这项真实世界证据研究通过在德国、奥地利和波兰进行针对性的谷歌和 Facebook 外展，考察了经历月经痉挛的女性的诊断模式、痛苦负担和临床试验准备情况。研究结果表明，尽管痛苦水平很高，但痛经的诊断存在很大的差距，并显示直接面向患者的沟通可以吸引在传统医疗环境中常常被忽视的广泛多样的人群。</p>
</div><p><strong>Key findings include:</strong></p>
<div class="lb-trans"><p><strong>主要发现包括：</strong></p>
</div><p><strong>Significant diagnostic gap despite high pain</strong></p>
<div class="lb-trans"><p><strong>尽管痛苦严重，但诊断差距显著</strong></p>
</div><p>Among respondents reporting symptoms consistent with dysmenorrhea, only 4.6% reported receiving a diagnosis even though 88.5% of affected women in Germany and Austria reported pain ≥6/10, with even higher pain levels observed in Poland.</p>
<div class="lb-trans"><p>在报告与痛经一致症状的受访者中，仅有 4.6% 的人报告获得了诊断，尽管 88.5% 的德国和奥地利受影响女性报告的疼痛评分≥6/10，波兰的疼痛水平甚至更高。</p>
</div><p><strong>Digital outreach accurately finds the right patients</strong> Targeted online campaigns demonstrated high specificity, with 94.6% of surveyed respondents meeting symptom criteria for dysmenorrhea, supporting DTP strategies as efficient tools for surfacing under-recognized patients.</p>
<div class="lb-trans"><p><strong>数字外展准确找到合适的患者</strong> 针对性的在线活动展示了高特异性，94.6% 的受访者符合痛经的症状标准，支持直接面向患者的策略作为识别未被充分认识患者的有效工具。</p>
</div><p><strong>Why diagnoses are missed</strong></p>
<div class="lb-trans"><p><strong>为何诊断被遗漏</strong></p>
</div><p>Approximately 90.3% of women had not sought medical advice, were unsure of their diagnosis, or said their symptoms weren't recognized as pathological. Among those diagnosed, nearly half with dysmenorrhea-like symptoms were labeled PMS only, highlighting potential under-recognition of dysmenorrhea.</p>
<div class="lb-trans"><p>大约 90.3% 的女性没有寻求医疗建议，或对自己的诊断不确定，或表示她们的症状未被视为病理性。在那些被诊断的患者中，近一半的痛经样症状患者仅被标记为经前综合症 (PMS)，突显了对痛经的潜在低识别率。</p>
</div><p><strong>PMS recognition is comparatively higher</strong></p>
<div class="lb-trans"><p><strong>PMS 的识别率相对较高</strong></p>
</div><p>Of diagnosed cases, 77.3% reported a PMS diagnosis, and 8.6% of women with PMS symptoms reported being diagnosed, nearly double the dysmenorrhea diagnosis rate in the same population.</p>
<div class="lb-trans"><p>在已诊断的病例中，77.3% 报告为 PMS 诊断，8.6% 的 PMS 症状女性报告被诊断，几乎是同一人群中痛经诊断率的两倍。</p>
</div><p>The findings reinforce SubjectWell's evidence-driven approach to patient-centric recruitment. By quantifying reach and diagnostic gaps, the study suggests DTP strategies can broaden clinical-trial awareness among women who are undiagnosed or not currently seeking care, while providing researchers with a more inclusive view of real-world symptom burden.</p>
<div class="lb-trans"><p>这些发现强化了 SubjectWell 以证据为驱动的以患者为中心的招募方法。通过量化覆盖范围和诊断差距，该研究表明，直接面向患者的策略可以扩大对未被诊断或当前未寻求护理的女性的临床试验意识，同时为研究人员提供更全面的真实世界症状负担视角。</p>
</div><p>&#34;We set out to understand how direct-to-patient communication could improve access for those experiencing menstrual pain,&#34; said Matthias Roos, Director of Scientific Affairs at SubjectWell. &#34;The data clearly show digital strategies can connect with the right patients quickly and respectfully, laying the groundwork for more inclusive women's health research.&#34;</p>
<div class="lb-trans"><p>“我们旨在了解直接面向患者的沟通如何改善经历月经疼痛者的获取，” SubjectWell 科学事务总监 Matthias Roos 表示。“数据清楚地表明，数字策略可以快速而尊重地与合适的患者建立联系，为更具包容性的女性健康研究奠定基础。”</p>
</div><p><em>This project was funded by and conducted in collaboration with Bionorica SE in the context of assessing clinical trial patient recruitment strategies and is acknowledged as such in the publication.</em></p>
<div class="lb-trans"><p><em>该项目由 Bionorica SE 资助并与其合作进行，旨在评估临床试验患者招募策略，并在出版物中得到了认可。</em></p>
</div><p>The full article is available here: https://www.jmir.org/2025/1/e68148</p>
<div class="lb-trans"><p>完整文章可在此查看：https://www.jmir.org/2025/1/e68148</p>
</div><p>For more information on SubjectWell's patient recruitment solutions, visit <strong>www.subjectwell.com</strong>.</p>
<div class="lb-trans"><p>有关 SubjectWell 患者招募解决方案的更多信息，请访问 <strong>www.subjectwell.com</strong>。</p>
</div><p><strong>About SubjectWell</strong></p>
<div class="lb-trans"><p><strong>关于 SubjectWell</strong></p>
</div><p>As the premier Patient Experience Platform, SubjectWell drives predictable trial enrollment and improves retention by enhancing the patient journey from protocol design through study completion. Powered by technology, global reach, full-service creative, and a suite of services to reduce site burden—SubjectWell drives intelligence and efficiency for sponsors, CROs, sites, and site networks. From protocol development through recruitment, enrollment, retention, and post-trial real-world evidence studies, SubjectWell supports the entire clinical lifecycle. To learn more, visit www.subjectwell.com.</p>
<div class="lb-trans"><p>作为首屈一指的患者体验平台，SubjectWell 通过增强患者旅程，从方案设计到研究完成，推动可预测的试验入组并改善留存。凭借技术、全球覆盖、全方位创意和一系列减少现场负担的服务，SubjectWell 为赞助商、CRO、现场和现场网络提供智能和效率。从方案开发到招募、入组、留存和试验后的真实世界证据研究，SubjectWell 支持整个临床生命周期。欲了解更多信息，请访问 www.subjectwell.com。</p>
</div><p><strong>MEDIA CONTACT:</strong></p>
<div class="lb-trans"><p><strong>媒体联系人：</strong></p>
</div><p>Alysha Swisher / Haylee Elmore</p>
<div class="lb-trans"><p>Alysha Swisher / Haylee Elmore</p>
</div><p>Interdependence PR</p>
<div class="lb-trans"><p>Interdependence PR</p>
</div><p>[email protected]</p>
<div class="lb-trans"><p>[email protected]</p>
</div><p>6023501455</p>
<div class="lb-trans"><p>6023501455</p>
</div><p>SOURCE SubjectWell</p>
<div class="lb-trans"><p>来源 SubjectWell</p>
</div><p><img src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjUwOTIzJk5ld3NJdGVtSWQ9UEg4MDIyOCZUcmFuc21pc3Npb25fSWQ9MjAyNTA5MjMwODU4UFJfTkVXU19VU1BSX19fX19QSDgwMjI4" alt="" original-src="https://rt.prnewswire.com/rt.gif?NewsItemId=PH80228&amp;Transmission_Id=202509230858PR_NEWS_USPR_____PH80228&amp;DateId=20250923"/></p>

08:58 ET
			
			
				Subjectwell Peer-Reviewed Paper Shows Major Diagnostic Gap In Dysmenorrhea; Direct-To-Patient Outreach Reaches Women Missed By Traditional Care

Subjectwell 的同行评审论文揭示了痛经诊断中的重大差距；直接面向患者的宣传接触到了传统护理未能覆盖的女性