<p>2025 年 10 月 3 日- 上午 11:53</p>
<p>史密斯 - 纳菲（Smith+Nephew）（纽约证券交易所代码：SNN；伦敦证券交易所代码：SN），全球医疗技术企业，欣然宣布来自阿米特·盖芬教授及其研究小组在《国际伤口杂志》上发表的令人振奋的新数据，展示了 ALLEVYN COMPLETE CARE 泡沫敷料的压力损伤预防机制及其吸收和分散摩擦和剪切力的能力。</p>
<p>压力损伤是由于长时间暴露于压力和剪切力的组合而导致的皮肤或下层组织的局部损伤。该开创性研究表明，新的 ALLEVYN COMPLETE CARE 泡沫敷料能够将 93% 的机械能吸收至其内部层。研究显示，该敷料能够在内部吸收和分散剪切力以及敷料层间的摩擦滑动。这一机制可以显著帮助减少已知会导致压力损伤的有害应力集中，这一临床负担每年给美国医疗系统带来超过 268 亿美元的成本。</p>
<p><img src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" alt="" original-src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg"/></p>
<p>通过使用摩擦能量吸收器有效性（FEAE）和有限元建模（FEM），结果确认了 ALLEVYN COMPLETE CARE 敷料在减轻机械负荷和保护下层软组织方面的作用机制。</p>
<p>“这些发现代表了压力损伤预防的重要进展，” 特拉维夫大学生物医学工程教授阿米特·盖芬表示。“ALLEVYN COMPLETE CARE 敷料的先进生物力学性能能够分散潜在有害的剪切力，从而帮助保护患者免受导致压力损伤的因素。”</p>
<p>“压力损伤是一个复杂且成本高昂的挑战，对患者和医疗系统都造成了沉重负担，” 史密斯 - 纳菲高级伤口管理部总裁罗希特·卡什亚普表示。“这篇出版物展示了 ALLEVYN COMPLETE CARE 泡沫敷料独特的作用机制及其分散剪切力的能力，帮助更多患者免受压力损伤的危害。”</p>
<p>ALLEVYN COMPLETE CARE 敷料将在今年晚些时候进入美国先进伤口护理市场，随后在 2026 年进入其他市场，适用于多种伤口的管理和压力损伤的预防。基于最初由 ALLEVYN LIFE 敷料建立的成功作用机制原则，新的 ALLEVYN COMPLETE CARE 泡沫敷料显示出摩擦能量吸收器有效性从 30-45% 提高至 93%。</p>
<p>要阅读完整出版物，请点击这里。</p>
<p>参考文献</p>
<ol>
<li>Orlova D, Orlov A, Gefen A. 新型软硅胶多层敷料在降低脚跟压力溃疡风险方面的保护效果。<em>国际伤口杂志</em>。2025；22(10)：e70764。</li>
<li>国家压力损伤咨询小组、欧洲压力溃疡咨询小组和泛太平洋压力损伤联盟。压力溃疡/损伤：定义和病因。在：压力溃疡/损伤的预防和治疗：临床实践指南。国际指南：第四版。艾米莉·海斯勒（编）。2025 年。[引用：2025 年 10 月 3 日]。可从：https://internationalguideline.com 获取。</li>
</ol>
<ol>
<li>Padula W V., &amp; Delarmente, B. A. (2019). 美国医院获得性压力损伤的国家成本。<em>伤口修复与再生， 27</em>(3), 329–335 WV, Delarmente BA. 美国医院获得性压力损伤的国家成本。<em>国际伤口杂志</em>。2019；16(3)：634-640。</li>
</ol>
<ol>
<li>Marché C, Creehan S, Gefen A. 摩擦能量吸收器有效性及其对多层敷料压力溃疡预防性能的影响。<em>国际伤口杂志</em>。2024；21(4)：e14871。</li>
</ol>
<p>- 结束 –</p>
<p><strong>咨询：</strong></p>
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<p><strong>关于史密斯 - 纳菲</strong></p>
<p>史密斯 - 纳菲是一家专注于软硬组织修复、再生和替代的医疗技术企业。我们的使命是通过技术帮助人们恢复身体和自信，打破生活的限制。我们称这一使命为 “无限生活”。我们的 17000 名员工每天都在实现这一使命，通过我们卓越的产品组合以及在骨科、运动医学与耳鼻喉科和先进伤口管理三个全球业务单元中发明和应用新技术，改变患者的生活。</p>
<p>史密斯 - 纳菲成立于 1856 年，位于英国赫尔，目前在约 100 个国家运营，2024 年年销售额达到 58 亿美元。史密斯 - 纳菲是 FTSE100 成分股（伦敦证券交易所代码：SN，纽约证券交易所代码：SNN）。除非上下文另有要求，否则 “集团” 和 “史密斯 - 纳菲” 用于指代史密斯 - 纳菲有限公司及其合并子公司。</p>
<p>有关史密斯 - 纳菲的更多信息，请访问 www.smith-nephew.com，并在 X、LinkedIn、Instagram 或 Facebook 上关注我们。</p>
<p><strong><em>前瞻性声明</em></strong></p>
<p>本文件可能包含前瞻性声明，这些声明可能会或可能不会被证明是准确的。例如，关于预期收入增长和交易利润率、市场趋势以及我们的产品管道的声明均属于前瞻性声明。诸如 “目标”、“计划”、“打算”、“预期”、“处于良好位置”、“相信”、“估计”、“期待”、“目标”、“考虑” 等短语通常旨在识别前瞻性声明。前瞻性声明涉及已知和未知的风险、不确定性以及其他重要因素，这些因素可能导致实际结果与声明中所表达或暗示的结果存在重大差异。对于 Smith+Nephew 而言，这些因素包括：欧洲和中东的冲突、我们服务市场的经济和金融状况，特别是影响医疗服务提供者、支付方和客户的因素；已建立和创新医疗设备的价格水平；医疗技术的发展；监管批准、报销决定或其他政府行动；产品缺陷或召回或质量管理系统的其他问题或未能遵守相关法规；与专利或其他索赔相关的诉讼；法律和财务合规风险及相关的调查、补救或执法行动；对我们或供应商的供应链或运营的干扰；对合格人员的竞争；战略行动，包括收购和处置，我们在尽职调查、评估和整合收购业务方面的成功；由于交易或我们为适应市场发展而在商业计划或组织中进行的其他变更可能导致的干扰；与医疗专业人员的关系；对信息技术和网络安全的依赖；由于自然灾害、天气和气候变化相关事件造成的干扰；客户和其他利益相关者的可持续性期望的变化；税收法规的变化；外汇波动的影响；以及影响我们或我们市场的众多其他事项，包括政治、经济、商业、竞争或声誉性质的事项。请参阅 Smith+Nephew 根据 1934 年美国证券交易法（及其修正案）向美国证券交易委员会提交的文件，包括 Smith+Nephew 最近的 20-F 表格年度报告，该报告可在 SEC 网站 www.sec.gov 上获取，以讨论某些这些因素。任何前瞻性声明均基于 Smith+Nephew 在声明日期可获得的信息。所有归因于 Smith+Nephew 的书面或口头前瞻性声明均以此警告为前提。Smith+Nephew 不承担任何更新或修订任何前瞻性声明以反映任何情况变化或 Smith+Nephew 预期变化的义务。</p>
<p>◊ Smith+Nephew 的商标。某些商标在美国专利和商标局注册。</p>
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<p>Smith+Nephew 宣布了新的科学数据，支持其 ALLEVYN COMPLETE CARE 泡沫敷料在预防压疮方面的应用。发表在《国际伤口杂志》上的研究显示，该敷料能够吸收 93% 的机械能，有效地消散导致压疮的摩擦和剪切力。这一创新旨在减少压疮对临床的负担，压疮每年给美国医疗系统带来的费用超过 268 亿美元。该敷料将在今年晚些时候在美国市场推出，并计划在 2026 年进一步扩展</p>

<p>10/03/2025 - 11:53 AM</p>
<div class="lb-trans"><p>2025 年 10 月 3 日- 上午 11:53</p>
</div><p>Smith+Nephew (NYSE:SNN; LSE:SN), the global medical technology business, is pleased to announce exciting new data from Professor Amit Gefen and his research group published in the <em>International Wound Journal</em>,1 demonstrating the pressure injury prevention mechanism of action of ALLEVYN COMPLETE CARE Foam Dressing and its ability to absorb and dissipate friction and shear forces.</p>
<div class="lb-trans"><p>史密斯 - 纳菲（Smith+Nephew）（纽约证券交易所代码：SNN；伦敦证券交易所代码：SN），全球医疗技术企业，欣然宣布来自阿米特·盖芬教授及其研究小组在《国际伤口杂志》上发表的令人振奋的新数据，展示了 ALLEVYN COMPLETE CARE 泡沫敷料的压力损伤预防机制及其吸收和分散摩擦和剪切力的能力。</p>
</div><p>Pressure injuries are localized damage to the skin or underlying tissue, resulting from prolonged exposure to pressure in combination with shear forces.2 This landmark study demonstrates that the new ALLEVYN COMPLETE CARE Foam Dressing absorbs 93% of mechanical energy into its internal layers. The study shows that the dressing absorbs and dissipates shear forces internally and layer-to-layer frictional sliding within the dressing. This mechanism of action can significantly help reduce the harmful stress concentrations that are known to cause pressure injuries, a clinical burden which costs the US healthcare system over $26.8bn every year.3</p>
<div class="lb-trans"><p>压力损伤是由于长时间暴露于压力和剪切力的组合而导致的皮肤或下层组织的局部损伤。该开创性研究表明，新的 ALLEVYN COMPLETE CARE 泡沫敷料能够将 93% 的机械能吸收至其内部层。研究显示，该敷料能够在内部吸收和分散剪切力以及敷料层间的摩擦滑动。这一机制可以显著帮助减少已知会导致压力损伤的有害应力集中，这一临床负担每年给美国医疗系统带来超过 268 亿美元的成本。</p>
</div><p><img src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg" alt="" original-src="https://ml-eu.globenewswire.com/Resource/Download/674c39be-7cd5-465d-80cf-75f3ec8160bb/allevyn-complete-care-family-shot-rgb-large-white-no-logos.jpg"/></p>
<p>By using both Frictional Energy Absorber Effectiveness (FEAE) and Finite Element Modelling (FEM), the results confirmed the mechanism of action of ALLEVYN COMPLETE CARE Dressing in mitigating mechanical loading and protecting underlying soft tissue.</p>
<div class="lb-trans"><p>通过使用摩擦能量吸收器有效性（FEAE）和有限元建模（FEM），结果确认了 ALLEVYN COMPLETE CARE 敷料在减轻机械负荷和保护下层软组织方面的作用机制。</p>
</div><p>“These findings represent a significant step forward in pressure injury prevention,” said Amit Gefen, Professor of Biomedical Engineering at Tel Aviv University. “ALLEVYN COMPLETE CARE Dressing's advanced biomechanical performance dissipates potentially harmful shear forces, which can help protect patients from factors that contribute to pressure injuries.”</p>
<div class="lb-trans"><p>“这些发现代表了压力损伤预防的重要进展，” 特拉维夫大学生物医学工程教授阿米特·盖芬表示。“ALLEVYN COMPLETE CARE 敷料的先进生物力学性能能够分散潜在有害的剪切力，从而帮助保护患者免受导致压力损伤的因素。”</p>
</div><p>''Pressure injuries are a complex and costly challenge, placing a heavy burden on both patients and healthcare systems,&#34; said Rohit Kashyap, President, Advanced Wound Management at Smith+Nephew. “This publication showcases the distinct mechanism of action of ALLEVYN COMPLETE CARE Foam Dressing and its ability to dissipate shear forces, helping to protect more patients from the harm of pressure injuries.”</p>
<div class="lb-trans"><p>“压力损伤是一个复杂且成本高昂的挑战，对患者和医疗系统都造成了沉重负担，” 史密斯 - 纳菲高级伤口管理部总裁罗希特·卡什亚普表示。“这篇出版物展示了 ALLEVYN COMPLETE CARE 泡沫敷料独特的作用机制及其分散剪切力的能力，帮助更多患者免受压力损伤的危害。”</p>
</div><p>ALLEVYN COMPLETE CARE Dressing will be launched into the US advanced wound care market later in the year, followed by subsequent markets throughout 2026, and is indicated for the management of a range of wounds and pressure injury prevention. Building on the successful mechanism of action principles originally established by ALLEVYN LIFE Dressing,4 the new ALLEVYN COMPLETE CARE Foam Dressing demonstrated an increased Frictional Energy Absorber Effectiveness, up from 30-45% to 93%.</p>
<div class="lb-trans"><p>ALLEVYN COMPLETE CARE 敷料将在今年晚些时候进入美国先进伤口护理市场，随后在 2026 年进入其他市场，适用于多种伤口的管理和压力损伤的预防。基于最初由 ALLEVYN LIFE 敷料建立的成功作用机制原则，新的 ALLEVYN COMPLETE CARE 泡沫敷料显示出摩擦能量吸收器有效性从 30-45% 提高至 93%。</p>
</div><p>To read the full publication, please click here.</p>
<div class="lb-trans"><p>要阅读完整出版物，请点击这里。</p>
</div><p>References</p>
<div class="lb-trans"><p>参考文献</p>
</div><ol>
<li>Orlova D, Orlov A, Gefen A. The Protective Efficacy of a New Soft Silicone Multi-Layer Dressing in Reducing the Heel Pressure Ulcer Risk. <em>Int Wound J</em>. 2025;22(10):e70764.</li>
<li>National Pressure Injury Advisory Panel, European Pressure Ulcer Advisory Panel and Pan Pacific Pressure Injury Alliance. Pressure Ulcers/Injuries: Definition and Etiology. In: Prevention and Treatment of Pressure Ulcers/Injuries: Clinical Practice Guideline. The International Guideline: Fourth Edition. Emily Haesler (Ed.). 2025. [cited: 3rd October 2025]. Available from: https://internationalguideline.com.</li>
</ol>
<div class="lb-trans"><ol>
<li>Orlova D, Orlov A, Gefen A. 新型软硅胶多层敷料在降低脚跟压力溃疡风险方面的保护效果。<em>国际伤口杂志</em>。2025；22(10)：e70764。</li>
<li>国家压力损伤咨询小组、欧洲压力溃疡咨询小组和泛太平洋压力损伤联盟。压力溃疡/损伤：定义和病因。在：压力溃疡/损伤的预防和治疗：临床实践指南。国际指南：第四版。艾米莉·海斯勒（编）。2025 年。[引用：2025 年 10 月 3 日]。可从：https://internationalguideline.com 获取。</li>
</ol>
</div><ol>
<li>Padula W V., &amp; Delarmente, B. A. (2019). The national cost of hospital-acquired pressure injuries in the United States. <em>Wound Repair and Regeneration, 27</em>(3), 329–335 WV, Delarmente BA. The national cost of hospital-acquired pressure injuries in the United States. <em>Int Wound J</em>. 2019;16(3):634-640..</li>
</ol>
<div class="lb-trans"><ol>
<li>Padula W V., &amp; Delarmente, B. A. (2019). 美国医院获得性压力损伤的国家成本。<em>伤口修复与再生， 27</em>(3), 329–335 WV, Delarmente BA. 美国医院获得性压力损伤的国家成本。<em>国际伤口杂志</em>。2019；16(3)：634-640。</li>
</ol>
</div><ol>
<li>Marché C, Creehan S, Gefen A. The frictional energy absorber effectiveness and its impact on the pressure ulcer prevention performance of multilayer dressings. <em>Int Wound J</em>. 2024;21(4):e14871.</li>
</ol>
<div class="lb-trans"><ol>
<li>Marché C, Creehan S, Gefen A. 摩擦能量吸收器有效性及其对多层敷料压力溃疡预防性能的影响。<em>国际伤口杂志</em>。2024；21(4)：e14871。</li>
</ol>
</div><p>- Ends –</p>
<div class="lb-trans"><p>- 结束 –</p>
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</div><p><strong>About Smith+Nephew</strong></p>
<div class="lb-trans"><p><strong>关于史密斯 - 纳菲</strong></p>
</div><p>Smith+Nephew is a portfolio medical technology business focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people’s bodies and their self-belief by using technology to take the limits off living. We call this purpose ‘Life Unlimited’. Our 17,000 employees deliver this mission every day, making a difference to patients’ lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global business units of Orthopaedics, Sports Medicine &amp; ENT and Advanced Wound Management.</p>
<div class="lb-trans"><p>史密斯 - 纳菲是一家专注于软硬组织修复、再生和替代的医疗技术企业。我们的使命是通过技术帮助人们恢复身体和自信，打破生活的限制。我们称这一使命为 “无限生活”。我们的 17000 名员工每天都在实现这一使命，通过我们卓越的产品组合以及在骨科、运动医学与耳鼻喉科和先进伤口管理三个全球业务单元中发明和应用新技术，改变患者的生活。</p>
</div><p>Founded in Hull, UK, in 1856, we now operate in around 100 countries and generated annual sales of $5.8 billion in 2024. Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN). The terms ‘Group’ and ‘Smith+Nephew’ are used to refer to Smith &amp; Nephew plc and its consolidated subsidiaries, unless the context requires otherwise.</p>
<div class="lb-trans"><p>史密斯 - 纳菲成立于 1856 年，位于英国赫尔，目前在约 100 个国家运营，2024 年年销售额达到 58 亿美元。史密斯 - 纳菲是 FTSE100 成分股（伦敦证券交易所代码：SN，纽约证券交易所代码：SNN）。除非上下文另有要求，否则 “集团” 和 “史密斯 - 纳菲” 用于指代史密斯 - 纳菲有限公司及其合并子公司。</p>
</div><p>For more information about Smith+Nephew, please visit www.smith-nephew.com and follow us on X, LinkedIn, Instagram or Facebook.</p>
<div class="lb-trans"><p>有关史密斯 - 纳菲的更多信息，请访问 www.smith-nephew.com，并在 X、LinkedIn、Instagram 或 Facebook 上关注我们。</p>
</div><p><strong><em>Forward-looking Statements</em></strong></p>
<div class="lb-trans"><p><strong><em>前瞻性声明</em></strong></p>
</div><p><em>This document may contain forward-looking statements that may or may not prove accurate. For example, statements regarding expected revenue growth and trading profit margins, market trends and our product pipeline are forward-looking statements. Phrases such as &#34;aim&#34;, &#34;plan&#34;, &#34;intend&#34;, &#34;anticipate&#34;, &#34;well-placed&#34;, &#34;believe&#34;, &#34;estimate&#34;, &#34;expect&#34;, &#34;target&#34;, &#34;consider&#34; and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other important factors that could cause actual results to differ materially from what is expressed or implied by the statements. For Smith+Nephew, these factors include: conflicts in Europe and the Middle East, economic and financial conditions in the markets we serve, especially those affecting healthcare providers, payers and customers; price levels for established and innovative medical devices; developments in medical technology; regulatory approvals, reimbursement decisions or other government actions; product defects or recalls or other problems with quality management systems or failure to comply with related regulations; litigation relating to patent or other claims; legal and financial compliance risks and related investigative, remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers; competition for qualified personnel; strategic actions, including acquisitions and disposals, our success in performing due diligence, valuing and integrating acquired businesses; disruption that may result from transactions or other changes we make in our business plans or organisation to adapt to market developments; relationships with healthcare professionals; reliance on information technology and cybersecurity; disruptions due to natural disasters, weather and climate change related events; changes in customer and other stakeholder sustainability expectations; changes in taxation regulations; effects of foreign exchange volatility; and numerous other matters that affect us or our markets, including those of a political, economic, business, competitive or reputational nature. Please refer to the documents that Smith+Nephew has filed with the U.S. Securities and Exchange Commission under the U.S. Securities Exchange Act of 1934, as amended, including Smith+Nephew's most recent annual report on Form 20-F, which is available on the SEC’s website at www. sec.gov, for a discussion of certain of these factors. Any forward-looking statement is based on information available to Smith+Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith+Nephew are qualified by this caution. Smith+Nephew does not undertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances or in Smith+Nephew's expectations.</em></p>
<div class="lb-trans"><p>本文件可能包含前瞻性声明，这些声明可能会或可能不会被证明是准确的。例如，关于预期收入增长和交易利润率、市场趋势以及我们的产品管道的声明均属于前瞻性声明。诸如 “目标”、“计划”、“打算”、“预期”、“处于良好位置”、“相信”、“估计”、“期待”、“目标”、“考虑” 等短语通常旨在识别前瞻性声明。前瞻性声明涉及已知和未知的风险、不确定性以及其他重要因素，这些因素可能导致实际结果与声明中所表达或暗示的结果存在重大差异。对于 Smith+Nephew 而言，这些因素包括：欧洲和中东的冲突、我们服务市场的经济和金融状况，特别是影响医疗服务提供者、支付方和客户的因素；已建立和创新医疗设备的价格水平；医疗技术的发展；监管批准、报销决定或其他政府行动；产品缺陷或召回或质量管理系统的其他问题或未能遵守相关法规；与专利或其他索赔相关的诉讼；法律和财务合规风险及相关的调查、补救或执法行动；对我们或供应商的供应链或运营的干扰；对合格人员的竞争；战略行动，包括收购和处置，我们在尽职调查、评估和整合收购业务方面的成功；由于交易或我们为适应市场发展而在商业计划或组织中进行的其他变更可能导致的干扰；与医疗专业人员的关系；对信息技术和网络安全的依赖；由于自然灾害、天气和气候变化相关事件造成的干扰；客户和其他利益相关者的可持续性期望的变化；税收法规的变化；外汇波动的影响；以及影响我们或我们市场的众多其他事项，包括政治、经济、商业、竞争或声誉性质的事项。请参阅 Smith+Nephew 根据 1934 年美国证券交易法（及其修正案）向美国证券交易委员会提交的文件，包括 Smith+Nephew 最近的 20-F 表格年度报告，该报告可在 SEC 网站 www.sec.gov 上获取，以讨论某些这些因素。任何前瞻性声明均基于 Smith+Nephew 在声明日期可获得的信息。所有归因于 Smith+Nephew 的书面或口头前瞻性声明均以此警告为前提。Smith+Nephew 不承担任何更新或修订任何前瞻性声明以反映任何情况变化或 Smith+Nephew 预期变化的义务。</p>
</div><p><em>◊</em> <em>Trademark of Smith+Nephew. Certain marks registered in US Patent and Trademark Office.</em></p>
<div class="lb-trans"><p>◊ Smith+Nephew 的商标。某些商标在美国专利和商标局注册。</p>
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<p><img src="https://imageproxy.pbkrs.com/https://ml-eu.globenewswire.com/media/NTIzZWNjMWEtNDQyMi00YWI3LWI0M2ItYzVmYmI3ZWRmMTI0LTEwMTMyMDQtMjAyNS0xMC0wMy1lbg==/tiny/Smith-Nephew-UK-Ltd.png" alt="" original-src="https://ml-eu.globenewswire.com/media/NTIzZWNjMWEtNDQyMi00YWI3LWI0M2ItYzVmYmI3ZWRmMTI0LTEwMTMyMDQtMjAyNS0xMC0wMy1lbg==/tiny/Smith-Nephew-UK-Ltd.png"/></p>

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