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<p>研究人员发现，日光浴床会对几乎所有皮肤造成严重的 DNA 损伤，这有助于解释为什么它们显著提高了黑色素瘤的风险，而黑色素瘤是最致命的皮肤癌形式。</p>
<p>领导西北大学黑色素瘤项目的 Pedram Gerami 博士多年来注意到，许多 50 岁以下有多发黑色素瘤的女性有使用日光浴床的历史。</p>
<p>为了研究这一点，他的团队回顾了大约 3000 名使用日光浴床的人的医疗记录，并与大约 3000 名从未使用过日光浴床的相似人群进行了比较。日光浴床用户中发现黑色素瘤的比例为 5.1%，而非用户为 2.1%。即使在考虑其他风险因素后，使用日光浴床与近三倍的黑色素瘤风险相关。</p>
<p>研究人员还发现，日光浴床用户更可能在通常受到阳光保护的部位（如下背部和臀部）发展黑色素瘤，这表明日光浴床造成的皮肤损伤比自然阳光更为广泛。</p>
<p>为了确认这一点，团队对个体皮肤细胞进行了先进的基因测试。他们检查了定期使用日光浴床的人和从未使用过的人所产生的色素细胞。他们发现，日光浴床用户的细胞有近两倍的基因突变和更多与癌症相关的变化。这些突变也出现在通常被覆盖的皮肤区域。</p>
<p>研究人员建议，过去经常使用日光浴床的人应进行全身皮肤检查，并与皮肤科医生讨论定期监测。</p>
<p>如有意见和反馈，请联系：editorial@rttnews.com</p>
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<p>研究人员发现，日光浴床会对几乎所有皮肤造成严重的 DNA 损伤，显著提高黑色素瘤的风险，而黑色素瘤是最致命的皮肤癌。由西北大学的 Pedram Gerami 博士领导的一项研究显示，使用日光浴床的人群相比于不使用者，黑色素瘤的风险几乎高出三倍。研究还发现，日光浴床造成的皮肤损伤比自然阳光更为广泛。研究人员建议曾经使用日光浴床的人定期进行全身皮肤检查</p>

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</div><p>Researchers found that tanning beds can cause serious DNA damage across almost all of the skin, helping explain why they sharply raise the risk of melanoma, the deadliest form of skin cancer.</p>
<div class="lb-trans"><p>研究人员发现，日光浴床会对几乎所有皮肤造成严重的 DNA 损伤，这有助于解释为什么它们显著提高了黑色素瘤的风险，而黑色素瘤是最致命的皮肤癌形式。</p>
</div><p>Dr Pedram Gerami, who leads a melanoma program at Northwestern University, noticed over many years that many women under 50 with multiple melanomas had a history of using tanning beds.</p>
<div class="lb-trans"><p>领导西北大学黑色素瘤项目的 Pedram Gerami 博士多年来注意到，许多 50 岁以下有多发黑色素瘤的女性有使用日光浴床的历史。</p>
</div><p>To study this, his team reviewed medical records of about 3,000 people who had used tanning beds and compared them with around 3,000 similar people who had never used them. Melanoma was found in 5.1 percent of tanning bed users, compared with 2.1 percent of non-users. Even after accounting for other risk factors, tanning bed use was linked to nearly three times higher melanoma risk.</p>
<div class="lb-trans"><p>为了研究这一点，他的团队回顾了大约 3000 名使用日光浴床的人的医疗记录，并与大约 3000 名从未使用过日光浴床的相似人群进行了比较。日光浴床用户中发现黑色素瘤的比例为 5.1%，而非用户为 2.1%。即使在考虑其他风险因素后，使用日光浴床与近三倍的黑色素瘤风险相关。</p>
</div><p>The researchers also found that tanning bed users were more likely to develop melanoma on areas such as the lower back and buttocks, which are normally protected from the sun, suggesting that tanning beds cause more widespread skin damage than natural sunlight.</p>
<div class="lb-trans"><p>研究人员还发现，日光浴床用户更可能在通常受到阳光保护的部位（如下背部和臀部）发展黑色素瘤，这表明日光浴床造成的皮肤损伤比自然阳光更为广泛。</p>
</div><p>To confirm this, the team used advanced genetic testing on individual skin cells. They examined pigment-producing cells from people who regularly used tanning beds and from those who never did. They found that cells from tanning bed users had almost twice as many genetic mutations and more cancer-related changes. These mutations were also found in skin areas that are usually covered.</p>
<div class="lb-trans"><p>为了确认这一点，团队对个体皮肤细胞进行了先进的基因测试。他们检查了定期使用日光浴床的人和从未使用过的人所产生的色素细胞。他们发现，日光浴床用户的细胞有近两倍的基因突变和更多与癌症相关的变化。这些突变也出现在通常被覆盖的皮肤区域。</p>
</div><p>The researchers advised that people who used tanning beds often in the past should get a full-body skin check and discuss regular monitoring with a dermatologist.</p>
<div class="lb-trans"><p>研究人员建议，过去经常使用日光浴床的人应进行全身皮肤检查，并与皮肤科医生讨论定期监测。</p>
</div><p>For comments and feedback contact: editorial@rttnews.com</p>
<div class="lb-trans"><p>如有意见和反馈，请联系：editorial@rttnews.com</p>
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研究发现，使用日光浴床会增加全身患黑色素瘤的风险