<div id="readability-page-1">Tonix Pharmaceuticals Holding Corp ( TNXP ). on Monday announced program updates on TNX-4800 (formerly known as mAb 2217LS), a long-acting human monoclonal antibody (mAb) that targets the outer surface protein A (OspA) of Borrelia burgdorferi, the causative agent of Lyme disease in humans. TNX-4800 is being developed for annual seasonal use, as one subcutaneous administration in the spring to protect against Lyme disease through fall, or the entire tick season in the U.S. There are no currently marketed U.S. Food and Drug Administration (FDA)-approved vaccines or prophylactics to protect against Lyme disease. Also Read: Valneva Posts Positive Lyme Vaccine Booster Results — Pfizer Targeting 2026 Regulatory Filings “We plan to meet with the FDA in 2026 to explore Phase 2/3 development options,” said Seth Lederman, CEO of Tonix Pharmaceuticals ( TNXP ). “We believe a controlled human infection model (CHIM) 3-5 study using Borrelia-infected ticks that mimics natural infection would be a potential path to demonstrating TNX-4800 efficacy for approval. We are on a path to have investigational product produced under Good Manufacturing Practices (GMP) available for testing early in 2027.” The company, in a press release on Monday, said approximately 70 million people who live, work, or vacation in areas of the U.S. in which Lyme disease is endemic could potentially benefit from pre-exposure prophylaxis. <h2>Pricing of Registered Direct Offering</h2> Concurrently, Tonix Pharmaceuticals ( TNXP ) announced a securities purchase agreement with Point72 for 615,025 shares at $16.26 per share and pre-funded warrants to purchase up to 615,025 shares at $16.259 per pre-funded warrant, with gross proceeds of approximately $20.0 million. The company will use the proceeds to fund the commercialization of its marketed products, the development of its product pipeline, and general working capital and corporate purposes. TNXP Price Action: Tonix Pharmaceuticals ( TNXP ) shares were up 0.80% at $16.39 at the time of publication on Monday, according to Benzinga Pro data. Read Next: <ul> <li>Sam Altman Says He’s ‘Envious of the Current Generation of 20-Year-Old Dropouts’</li> </ul> Image via Shutterstock</div>

Tonix 医药控股

Tonix Pharmaceuticals 宣布了关于 TNX-4800 的最新进展，这是一种用于预防莱姆病的长效单克隆抗体，计划在 2026 年与 FDA 进行讨论。该抗体旨在每年使用，以在蜱虫季节保护人们免受莱姆病的侵害。公司还透露与 Point72 签署了一项 2000 万美元的证券购买协议，以支持产品的商业化和开发。公告发布后，TNXP 股价上涨 0.80%，至 16.39 美元

Tonix 公司推出了一种每年一次的莱姆病预防抗体，并计划在 2026 年与美国食品药品监督管理局（FDA）进行谈判