美国股指期货今晨走低，纳斯达克期货在周四因科技板块获利了结和主要服装及基础设施巨头的企业指引令人失望而下跌约 0.89%。
ADC Therapeutics SA (NYSE: ADCT] 的股票在盘前交易中因试验安全问题暴跌。
此次大规模抛售发生在其第三阶段 LOTIS-5 试验的顶线数据公布之后，该试验评估了其 FDA 批准的淋巴瘤疗法 Zynlonta 的组合方案。
Zynlonta 是一种抗体药物偶联物，采用加速 FDA 批准路径进行销售，因此必须提供积极的确认数据才能继续在美国市场上销售。尽管这家瑞士生物技术公司表示，该试验在重度预处理的复发/难治性 DLBCL 患者中成功达到了主要的无进展生存期终点，并具有统计学意义，但试验的潜在细节引发了抛售。
ADC Therapeutics 的股票在盘前交易中下跌 50.67%，至 1.52 美元。
以下是一些在盘前交易中下跌的其他股票：
<ul>
<li>Julong Holding(NASDAQ: JLHL) 的股票在盘前交易中暴跌 36.65%，至 21.82 美元，此前宣布以大幅折扣定价 150 百万美元的增发普通股。</li>
<li>Apartment Investment and Management Company(NYSE: AIV) 在盘前交易中下跌 28.98%，至 3.04 美元，此前发布了悲观的运营更新，并在一家主要华尔街券商的评级中从买入下调至持有，原因是多户型租金增长放缓。</li>
<li>PVH Corp(NYSE: PVH) 在盘前交易中暴跌 22.10%，至 76.35 美元，此前报告第一季度收入未达预期，并大幅下调全年销售指引，低于分析师共识，原因是欧洲和亚洲的消费者可支配支出趋势疲软。</li>
<li>Netskope Inc(NASDAQ: NTSK) 在盘前交易中下跌 19.04%，至 10.04 美元，此前报告季度业绩喜忧参半，并发布保守的账单预测，未能达到高端网络安全行业的增长预期。</li>
<li>Air Global PLC(NASDAQ: AIIR) 在周四的盘前交易中下跌 15.95%，至 5.80 美元。</li>
<li>Broadcom Inc(NASDAQ: AVGO) 在盘前交易中下跌 14.87%，至 407.99 美元，此前一家知名华尔街分析师团队发布了谨慎的报告，指出定制 AI ASIC 处理器在财政年度后半段可能面临短期交付瓶颈和产能限制。</li>
<li>3D Systems Corp(NYSE: DDD) 在盘前交易中下跌 14.69%，至 3.08 美元，此前报告第一季度亏损超出预期，并宣布了一项包括裁员 10% 的重组计划。</li>
<li>Boost Run Inc(NASDAQ: BRUN) 在周四的盘前交易中下跌 13.36%，至 33.01 美元。</li>
</ul>

休森

ADCT

3D系统

JLHL

NTSK

美国股指期货在盘前交易中因科技股获利了结和疲弱的指引而下跌。ADC Therapeutics 股价因试验安全问题暴跌 50.67%，而 Julong Holding 在进行折价公开发行后下跌 36.65%。其他下跌的公司包括 Apartment Investment（被下调评级）、PVH Corp（未达收入/指引）、Netskope（保守预测）、Broadcom（交付瓶颈）和 3D Systems（亏损扩大/重组）

U.S. stock futures were lower this morning, with the Nasdaq futures falling around 0.89% on Thursday following tech sector profit-taking and disappointing corporate guidance from major apparel and infrastructure giants.
<div class="lb-trans">美国股指期货今晨走低，纳斯达克期货在周四因科技板块获利了结和主要服装及基础设施巨头的企业指引令人失望而下跌约 0.89%。
</div>Shares of ADC Therapeutics SA (NYSE: ADCT) plummeted in pre-market trading due to trial safety concerns.
<div class="lb-trans">ADC Therapeutics SA (NYSE: ADCT] 的股票在盘前交易中因试验安全问题暴跌。
</div>The massive sell-off came after the top-line data from its Phase 3 LOTIS-5 trial, which evaluates a combination regimen of its FDA-approved lymphoma therapy, Zynlonta.
<div class="lb-trans">此次大规模抛售发生在其第三阶段 LOTIS-5 试验的顶线数据公布之后，该试验评估了其 FDA 批准的淋巴瘤疗法 Zynlonta 的组合方案。
</div>Zynlonta is an antibody-drug conjugate is sold under an accelerated FDA approval pathway, making positive confirmatory data mandatory for it to stay on the U.S. market. Though the Swiss biotech stated that the trial successfully hit its primary progression-free survival endpoint with statistical significance in heavily pre-treated r/r DLBCL patients, underlying trial details triggered the sell-off.
<div class="lb-trans">Zynlonta 是一种抗体药物偶联物，采用加速 FDA 批准路径进行销售，因此必须提供积极的确认数据才能继续在美国市场上销售。尽管这家瑞士生物技术公司表示，该试验在重度预处理的复发/难治性 DLBCL 患者中成功达到了主要的无进展生存期终点，并具有统计学意义，但试验的潜在细节引发了抛售。
</div>ADC Therapeutics shares dipped 50.67% to $1.52 in pre-market trading.
<div class="lb-trans">ADC Therapeutics 的股票在盘前交易中下跌 50.67%，至 1.52 美元。
</div>Here are some other stocks moving lower in pre-market trading:
<div class="lb-trans">以下是一些在盘前交易中下跌的其他股票：
</div><ul>
<li>Julong Holding(NASDAQ: JLHL) shares tumbled 36.65% to $21.82 in pre-market trading after announcing the pricing of an upsized $150 million public offering of common stock at a steep discount to its previous close.</li>
<li>Apartment Investment and Management Company(NYSE: AIV) declined 28.98% to $3.04 in pre-market trading following a downbeat operational update and a downgrade from Buy to Hold at a major Wall Street brokerage citing slowing multi-family rent growth.</li>
<li>PVH Corp(NYSE: PVH) plummeted 22.10% to $76.35 in pre-market trading after reporting a first-quarter revenue miss and lowering its full-year sales guidance significantly below analyst consensus due to weak consumer discretionary spending trends in Europe and Asia.</li>
<li>Netskope Inc(NASDAQ: NTSK) plunged 19.04% to $10.04 in pre-market trading after reporting mixed quarterly results and a conservative billings forecast that fell short of premium cybersecurity sector growth expectations.</li>
<li>Air Global PLC(NASDAQ: AIIR) slipped 15.95% to $5.80 in pre-market trading on Thursday.</li>
<li>Broadcom Inc(NASDAQ: AVGO) declined 14.87% to $407.99 in pre-market trading after a prominent Wall Street analyst team issued a cautious note flagging potential short-term delivery bottlenecks and capacity constraints for custom AI ASIC processors through the latter half of the fiscal year.</li>
<li>3D Systems Corp(NYSE: DDD) fell 14.69% to $3.08 in pre-market trading after reporting wider-than-expected first-quarter losses and announcing a restructuring plan that includes a 10% workforce reduction.</li>
<li>Boost Run Inc(NASDAQ: BRUN) declined 13.36% to $33.01 in pre-market trading on Thursday.</li>
</ul>
<div class="lb-trans"><ul>
<li>Julong Holding(NASDAQ: JLHL) 的股票在盘前交易中暴跌 36.65%，至 21.82 美元，此前宣布以大幅折扣定价 150 百万美元的增发普通股。</li>
<li>Apartment Investment and Management Company(NYSE: AIV) 在盘前交易中下跌 28.98%，至 3.04 美元，此前发布了悲观的运营更新，并在一家主要华尔街券商的评级中从买入下调至持有，原因是多户型租金增长放缓。</li>
<li>PVH Corp(NYSE: PVH) 在盘前交易中暴跌 22.10%，至 76.35 美元，此前报告第一季度收入未达预期，并大幅下调全年销售指引，低于分析师共识，原因是欧洲和亚洲的消费者可支配支出趋势疲软。</li>
<li>Netskope Inc(NASDAQ: NTSK) 在盘前交易中下跌 19.04%，至 10.04 美元，此前报告季度业绩喜忧参半，并发布保守的账单预测，未能达到高端网络安全行业的增长预期。</li>
<li>Air Global PLC(NASDAQ: AIIR) 在周四的盘前交易中下跌 15.95%，至 5.80 美元。</li>
<li>Broadcom Inc(NASDAQ: AVGO) 在盘前交易中下跌 14.87%，至 407.99 美元，此前一家知名华尔街分析师团队发布了谨慎的报告，指出定制 AI ASIC 处理器在财政年度后半段可能面临短期交付瓶颈和产能限制。</li>
<li>3D Systems Corp(NYSE: DDD) 在盘前交易中下跌 14.69%，至 3.08 美元，此前报告第一季度亏损超出预期，并宣布了一项包括裁员 10% 的重组计划。</li>
<li>Boost Run Inc(NASDAQ: BRUN) 在周四的盘前交易中下跌 13.36%，至 33.01 美元。</li>
</ul>
</div>

ADC Therapeutics Posts Downbeat Q1 Earnings, Joins Julong Holding And Other Big Stocks Moving Lower In Thursday's Pre-Market Session

benzinga_article

Apartment Investment

ADC Therapeutics SA

Julong

Netskope

博通

ADC Therapeutics 公布了低迷的第一季度收益，加入了 Julong Holding 和其他在周四盘前交易中下跌的大盘股行列