<p>作者：Jaimy Lee</p>
<p>投資者史蒂夫·艾斯曼正在接受乳腺癌治療。</p>
<p>史蒂夫·艾斯曼，這位因在全球金融危機前對美國房地產市場做空而聞名的交易員，表示他正在接受乳腺癌治療。</p>
<p>史蒂夫·艾斯曼是一位對沖基金交易員，以在 2007-09 年經濟衰退前成功做空房地產市場而聞名於華爾街。他在金融危機前的經歷在暢銷書《大空頭》中詳細描述，該書被改編成了一部熱門電影。</p>
<p>週四，艾斯曼在 CNBC 上講述了他健康狀況的感人故事，稱他患有乳腺癌並正在接受治療。根據美國癌症協會的數據，男性乳腺癌的診斷不到 1%，而且通常發生在 60 至 70 歲的男性身上。</p>
<p>在採訪中，艾斯曼，現年 60 出頭，表示他的一位腫瘤科醫生朋友在他們 6 月打完壁球后，在健身房的更衣室裏注意到他左側乳房的皮膚刺激。</p>
<p>“他看着我，説，‘那是什麼？’ 我回答，‘什麼？’” 艾斯曼説。“他真的走過來，開始在更衣室給我做乳房檢查。”</p>
<p>“我立刻就知道了，” 他的朋友羅伯特·蓋爾芬德説，他在紐約市經營一個輸液中心網絡。</p>
<p>他催促艾斯曼立即進行乳腺 X 光檢查。隨後，艾斯曼被診斷出，進行了雙側乳腺切除手術，並接受兩種化療：紫杉醇和 AC（阿黴素和環磷酰胺）。他將在本月完成化療，並將在 1 月開始放療。</p>
<p>“女性經常面臨這種情況，” 艾斯曼説。“我提到這個的原因是，雖然男性罕見，但並非聞所未聞。”</p>
<p>醫生和研究人員對男性乳腺癌的瞭解不如女性，但這一情況正在慢慢改變。醫生們意識到某些因素可能會增加男性患病的風險，包括年齡較大或從父母那裏遺傳 BRCA 基因突變。</p>
<p>擁有突變的 BRCA 基因會增加多種癌症的風險，包括乳腺癌、卵巢癌、前列腺癌和胰腺癌。阿什肯納茲猶太人和冰島裔人羣更可能擁有突變的 BRCA 基因，這也是一些女性選擇進行預防性乳腺切除或子宮切除的原因。這也是男性患乳腺癌的最大已知風險因素，波士頓 Dana-Farber 癌症研究所的乳腺腫瘤學家哈爾·伯斯坦告訴 MarketWatch。伯斯坦並未參與艾斯曼的治療。</p>
<p>BRCA 基因有兩種類型。根據 2022 年發表在《臨牀腫瘤學雜誌》上的一項研究，BRCA1 突變會使男性在 70 歲時患乳腺癌的風險增加至 1.2%，而 BRCA2 突變則可能使風險增加至 7.1%。</p>
<p>根據 2018 年發表在《新英格蘭醫學雜誌》上的一項研究，男性乳腺癌的生存率通常低於女性。這可能與診斷年齡以及男性並不定期接受乳腺癌篩查有關。當男性發現自己有腫塊時，癌症往往已經處於更晚期。</p>
<p>“男性需要提高警惕，” 艾斯曼説。</p>
<p>在過去十年左右，針對基因突變影響癌症風險的人羣，市場上出現了一波更好的癌症檢測和治療方法。阿斯利康（AstraZeneca）的 Lynparza 是 2014 年首次獲批專門治療 BRCA 突變卵巢癌的藥物。現在它也被批准用於治療相關的乳腺癌，有時也用於男性。人們對男性乳腺癌的認識也在不斷提高，越來越多的研究人員現在開始招募男性參與乳腺癌臨牀試驗。</p>
<p>“迄今為止，男性乳腺癌治療幾乎沒有隨機試驗報告，” 伯斯坦説。“我們借鑑了治療女性乳腺癌的所有經驗。”</p>
<p>當名人或其他知名人士如艾斯曼披露醫療診斷時，有時會導致所謂的 “安吉麗娜效應”，指的是在演員安吉麗娜·朱莉在 2013 年分享她因攜帶 BRCA1 基因突變而進行預防性雙側乳腺切除後，BRCA 檢測率的增加。一個知名人士是馬修·諾爾斯，碧昂絲的父親，他曾表示自己被診斷出乳腺癌並攜帶 BRCA2 突變。</p>
<p>艾斯曼在 CNBC 採訪中沒有説明他是否攜帶 BRCA 突變，他呼籲男性在注意到任何變化時尋求醫療幫助。</p>
<p>“只需檢查一下，” 他説。“在乳腺 X 光檢查後，醫生對我説，‘你的朋友救了你的命。’”</p>
<p>-Jaimy Lee</p>
<p>本文由 MarketWatch 創作，MarketWatch 由道瓊斯公司運營。MarketWatch 與道瓊斯新聞通訊和《華爾街日報》獨立出版。</p>
<p>（完）道瓊斯新聞通訊</p>
<p>12-14-25 0939ET</p>

<p>史蒂夫·艾斯曼因在《大空頭》中的角色而聞名，目前正在接受乳腺癌治療，這在男性中是一種罕見的疾病。在朋友的觀察後被診斷出，艾斯曼進行了雙側乳腺切除手術，並正在接受化療。男性乳腺癌的瞭解程度較低，但人們的意識正在提高。艾斯曼呼籲男性對任何變化尋求醫療建議，強調早期發現的重要性</p>

<p>By Jaimy Lee</p>
<div class="lb-trans"><p>作者：Jaimy Lee</p>
</div><p>The investor Steve Eisman is undergoing treatment for breast cancer.</p>
<div class="lb-trans"><p>投資者史蒂夫·艾斯曼正在接受乳腺癌治療。</p>
</div><p>Steve Eisman, the trader known for betting against the U.S. housing market before the global financial crisis, said he is undergoing treatment for breast cancer.</p>
<div class="lb-trans"><p>史蒂夫·艾斯曼，這位因在全球金融危機前對美國房地產市場做空而聞名的交易員，表示他正在接受乳腺癌治療。</p>
</div><p>Steve Eisman is a hedge-fund trader best known on Wall Street for successfully betting against the housing market before the recession of 2007-09. His experiences in the lead-up to the financial crisis were detailed in &#34;The Big Short,&#34; a bestselling book that was made into a hit movie.</p>
<div class="lb-trans"><p>史蒂夫·艾斯曼是一位對沖基金交易員，以在 2007-09 年經濟衰退前成功做空房地產市場而聞名於華爾街。他在金融危機前的經歷在暢銷書《大空頭》中詳細描述，該書被改編成了一部熱門電影。</p>
</div><p>On Thursday, Eisman went on CNBC and told a moving story about his health, saying he has breast cancer and is undergoing treatment for the disease. Fewer than 1% of breast cancer diagnoses occur in men, and when they do, it's usually in men who are between the ages of 60 and 70, according to the American Cancer Society.</p>
<div class="lb-trans"><p>週四，艾斯曼在 CNBC 上講述了他健康狀況的感人故事，稱他患有乳腺癌並正在接受治療。根據美國癌症協會的數據，男性乳腺癌的診斷不到 1%，而且通常發生在 60 至 70 歲的男性身上。</p>
</div><p>In the interview, Eisman, who is in his early 60s, said that a friend who is an oncologist noticed a skin irritation on his left breast while they were in the gym locker room after playing squash in June.</p>
<div class="lb-trans"><p>在採訪中，艾斯曼，現年 60 出頭，表示他的一位腫瘤科醫生朋友在他們 6 月打完壁球后，在健身房的更衣室裏注意到他左側乳房的皮膚刺激。</p>
</div><p>&#34;He looks at me, and he said, 'What's that? And I go, 'What's what?'&#34; Eisman said. &#34;And he literally walks over to me and starts giving me a breast exam in the locker room.&#34;</p>
<div class="lb-trans"><p>“他看着我，説，‘那是什麼？’ 我回答，‘什麼？’” 艾斯曼説。“他真的走過來，開始在更衣室給我做乳房檢查。”</p>
</div><p>&#34;I knew immediately,&#34; said his friend, Robert Gelfand, who runs a network of infusion centers in New York City.</p>
<div class="lb-trans"><p>“我立刻就知道了，” 他的朋友羅伯特·蓋爾芬德説，他在紐約市經營一個輸液中心網絡。</p>
</div><p>He urged Eisman to get a mammogram right away. From there, Eisman was diagnosed, underwent a double mastectomy and is being treated with two types of chemotherapy: Taxol and AC, or Adriamycin and cyclophosphamide. He will finish chemo this month and start radiation therapy in January.</p>
<div class="lb-trans"><p>他催促艾斯曼立即進行乳腺 X 光檢查。隨後，艾斯曼被診斷出，進行了雙側乳腺切除手術，並接受兩種化療：紫杉醇和 AC（阿黴素和環磷酰胺）。他將在本月完成化療，並將在 1 月開始放療。</p>
</div><p>&#34;Women face this all the time,&#34; Eisman said. &#34;The reason why I'm mentioning this is that it's rare for men, but it's not unheard of.&#34;</p>
<div class="lb-trans"><p>“女性經常面臨這種情況，” 艾斯曼説。“我提到這個的原因是，雖然男性罕見，但並非聞所未聞。”</p>
</div><p>Doctors and researchers don't know as much about breast cancer in men as they do in women, but that's slowly starting to change. Physicians are aware that certain factors can elevate a man's risk of getting the disease, including being older or inheriting a BRCA gene mutation from a parent.</p>
<div class="lb-trans"><p>醫生和研究人員對男性乳腺癌的瞭解不如女性，但這一情況正在慢慢改變。醫生們意識到某些因素可能會增加男性患病的風險，包括年齡較大或從父母那裏遺傳 BRCA 基因突變。</p>
</div><p>Having a mutated BRCA gene increases the risk of several cancers, including breast, ovarian, prostate and pancreatic. People of Ashkenazi Jewish and Icelandic descent are more likely to have a mutated BRCA gene, and it's one reason some women undergo preventive mastectomies or hysterectomies. It's also the largest known risk factor for men who get breast cancer, Hal Burstein, a breast oncologist at the Dana-Farber Cancer Institute in Boston, told MarketWatch. Burstein is not involved in Eisman's care.</p>
<div class="lb-trans"><p>擁有突變的 BRCA 基因會增加多種癌症的風險，包括乳腺癌、卵巢癌、前列腺癌和胰腺癌。阿什肯納茲猶太人和冰島裔人羣更可能擁有突變的 BRCA 基因，這也是一些女性選擇進行預防性乳腺切除或子宮切除的原因。這也是男性患乳腺癌的最大已知風險因素，波士頓 Dana-Farber 癌症研究所的乳腺腫瘤學家哈爾·伯斯坦告訴 MarketWatch。伯斯坦並未參與艾斯曼的治療。</p>
</div><p>There are two types of BRCA genes. A BRCA1 mutation raises the risk of breast cancer in men by up to 1.2% by age 70, while a BRCA2 mutation can increase the risk by up to 7.1%, according to a study published in 2022 in the Journal of Clinical Oncology.</p>
<div class="lb-trans"><p>BRCA 基因有兩種類型。根據 2022 年發表在《臨牀腫瘤學雜誌》上的一項研究，BRCA1 突變會使男性在 70 歲時患乳腺癌的風險增加至 1.2%，而 BRCA2 突變則可能使風險增加至 7.1%。</p>
</div><p>Survival rates for men with breast cancer tend to be lower than for women, according to a 2018 study published in the New England Journal of Medicine. This is likely due to the age of diagnosis and the fact that men aren't regularly screened for breast cancer. By the time a man has a lump that he can feel, the cancer is often at a more advanced stage.</p>
<div class="lb-trans"><p>根據 2018 年發表在《新英格蘭醫學雜誌》上的一項研究，男性乳腺癌的生存率通常低於女性。這可能與診斷年齡以及男性並不定期接受乳腺癌篩查有關。當男性發現自己有腫塊時，癌症往往已經處於更晚期。</p>
</div><p>&#34;There's a need for men to be aware,&#34; Eisman said.</p>
<div class="lb-trans"><p>“男性需要提高警惕，” 艾斯曼説。</p>
</div><p>Over the last decade or so, a wave of better cancer tests and treatments have come to market for people with gene mutations that affect cancer risk. AstraZeneca's (AZN) Lynparza was the first drug to specifically treat BRCA-mutated ovarian cancer when it was approved in 2014. It's now approved to treat related breast cancers and is sometimes used to treat men. There's also growing awareness about breast cancer in men, and more researchers are now enrolling men in breast cancer trials.</p>
<div class="lb-trans"><p>在過去十年左右，針對基因突變影響癌症風險的人羣，市場上出現了一波更好的癌症檢測和治療方法。阿斯利康（AstraZeneca）的 Lynparza 是 2014 年首次獲批專門治療 BRCA 突變卵巢癌的藥物。現在它也被批准用於治療相關的乳腺癌，有時也用於男性。人們對男性乳腺癌的認識也在不斷提高，越來越多的研究人員現在開始招募男性參與乳腺癌臨牀試驗。</p>
</div><p>&#34;There have been essentially no randomized trials in the treatment of male breast cancer that have reported to date,&#34; Burstein said. &#34;We take all the lessons from treating women with breast cancer.&#34;</p>
<div class="lb-trans"><p>“迄今為止，男性乳腺癌治療幾乎沒有隨機試驗報告，” 伯斯坦説。“我們借鑑了治療女性乳腺癌的所有經驗。”</p>
</div><p>When celebrities or other well-known figures like Eisman disclose medical diagnoses, it sometimes results in what's known as the &#34;Angelina effect,&#34; which refers to the increase in BRCA testing rates after actor Angelina Jolie shared in 2013 that she had a preventive double mastectomy upon learning she carried a BRCA1 gene mutation. One well-known person who has said he was diagnosed with breast cancer and has the BRCA2 mutation is Matthew Knowles, Beyoncé's father.</p>
<div class="lb-trans"><p>當名人或其他知名人士如艾斯曼披露醫療診斷時，有時會導致所謂的 “安吉麗娜效應”，指的是在演員安吉麗娜·朱莉在 2013 年分享她因攜帶 BRCA1 基因突變而進行預防性雙側乳腺切除後，BRCA 檢測率的增加。一個知名人士是馬修·諾爾斯，碧昂絲的父親，他曾表示自己被診斷出乳腺癌並攜帶 BRCA2 突變。</p>
</div><p>Eisman, who didn't say whether he has the BRCA mutation during the CNBC interview, urged men to seek medical care if they notice any changes.</p>
<div class="lb-trans"><p>艾斯曼在 CNBC 採訪中沒有説明他是否攜帶 BRCA 突變，他呼籲男性在注意到任何變化時尋求醫療幫助。</p>
</div><p>&#34;Just check it out,&#34; he said. &#34;After the mammogram, the doctor said to me, 'Your friend saved your life.'&#34;</p>
<div class="lb-trans"><p>“只需檢查一下，” 他説。“在乳腺 X 光檢查後，醫生對我説，‘你的朋友救了你的命。’”</p>
</div><p>-Jaimy Lee</p>
<div class="lb-trans"><p>-Jaimy Lee</p>
</div><p>This content was created by MarketWatch, which is operated by Dow Jones &amp; Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.</p>
<div class="lb-trans"><p>本文由 MarketWatch 創作，MarketWatch 由道瓊斯公司運營。MarketWatch 與道瓊斯新聞通訊和《華爾街日報》獨立出版。</p>
</div><p>(END) Dow Jones Newswires</p>
<div class="lb-trans"><p>（完）道瓊斯新聞通訊</p>
</div><p>12-14-25 0939ET</p>
<div class="lb-trans"><p>12-14-25 0939ET</p>
</div>

一場壁球比賽拯救了這位著名交易員的生命。男性乳腺癌的普遍程度如何？