<div><div></div><div>On October 28, 2025, Tourmaline Bio, Inc. announced the resignation of several board members and executives following the consummation of a merger. These changes were part of the merger agreement and not due to any disagreements with the company.<div><table><tbody><tr><td>Individual</td><td>Caley Castelein, M.D.</td><td>Aaron Kantoff</td><td>Sandeep Kulkarni, M.D.</td><td>Mark McDade</td><td>Clay Siegall, Ph.D.</td><td>Sapna Srivastava, Ph.D.</td><td>Parvinder Thiara</td><td>Ryan Robinson</td><td>Brad Middlekauff, J.D.</td><td>Susan Dana Jones, Ph.D.</td><td>Kevin Johnson, Ph.D.</td><td>John McKenna</td><td>Eduard Marti</td></tr><tr><td>Role</td><td>Board Member</td><td>Board Member</td><td>CEO</td><td>Board Member</td><td>Board Member</td><td>Board Member</td><td>Board Member</td><td>CFO</td><td>Chief Business Officer and General Counsel</td><td>CTO</td><td>Chief Regulatory Officer</td><td>President</td><td>Vice President and Treasurer</td></tr><tr><td>Type of Change</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Resigned</td><td>Appointed</td><td>Appointed</td></tr><tr><td>Effective Date</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td><td>Oct 28, 2025</td></tr><tr><td>Reason</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td><td>Merger Agreement</td></tr><tr><td>Replacement Info</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>N/A</td><td>N/A</td></tr><tr><td>Background Details</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>N/A</td><td>See Schedule I</td><td>See Schedule I</td></tr><tr><td>Board/Committee Role Changes</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td><td>Not disclosed</td></tr></tbody></table></div>Original SEC Filing: Tourmaline Bio, Inc. [ TRML ] - 8-K - Oct. 28, 2025<section>Disclaimer<div>This is an AI-powered summary. It may contain inaccuracies. Consider verifying important information with the source. Please note this summary is solely based on documents filed with the SEC.</div></section></div></div>

TRML

Tourmaline Bio, Inc. announced the resignation of several board members and executives on October 28, 2025, following a merger. The resignations were part of the merger agreement and not due to disagreements. Key resignations include the CEO, CFO, and other board members, effective the same date. Replacement information was not disclosed.

Tourmaline Bio Announces Board and Executive Resignations Following Merger