U.S. stocks developed mixed on Tuesday, with the Dow Jones Industrial Average breaking new highs, reaching 50,512 points, closing up 52 points or 0.1% at 50,188 points. The S&amp;P 500 fell 23 points or 0.33% to 6,941 points; the Nasdaq dropped 135 points or 0.59% to 23,102 points; the Golden Dragon Index, reflecting the performance of Chinese concept stocks, rose 0.87% to 7,885 points.Among major tech stocks, Tesla rose 1.89%, NVIDIA fell 0.79%, Apple dropped 0.34%, Microsoft decreased 0.08%, Alphabet fell 1.77%, Amazon dropped 0.84%, Meta fell 0.96%, and Broadcom decreased 1.02%.According to reports, the response to Alphabet's century bond subscription was ideal, with the dollar bond portion receiving over $100 billion in subscriptions. The £1 billion century bond (approximately $1.4 billion) was oversubscribed nearly 10 times.Strategy's stock price fell nearly 4%, with the company's founder stating that even if Bitcoin drops 90% in the next four years, Strategy will not be forced to sell Bitcoin but will choose to address debt pressure through refinancing.<h2>Tech stocks mixed, Tencent down over 1%</h2>In Hong Kong stocks, the Hang Seng Index opened up 63 points at 27,246 points. Tech stocks developed mixed, with Tencent (700) down 1.45%; Alibaba (9988) up 0.49%; Meituan (3690) down 0.45%.WUXI BIO (2269) expects a 46.3% year-on-year increase in net profit to HKD 4.908 billion, with the stock price opening up 3.54%. SMIC (981) announced a net profit of $173 million in the fourth quarter of last year, a year-on-year increase of 60.7%, with the stock price opening down 2.3%. PCCW (008) fell nearly 1%, with last year's consolidated EBITDA growing 3% year-on-year to HKD 13.29 billion.Regarding the northbound capital flow, on Thursday, net purchases of Hong Kong stocks amounted to HKD 84.8 million. Meituan (3690), CNOOC (883), and SMIC (981) received net purchases of HKD 546 million, HKD 420 million, and HKD 376 million, respectively; Tencent (700), Pop Mart (9992), and Zhaojin Mining (1818) faced net sales of HKD 1.402 billion, HKD 235 million, and HKD 221 million, respectively

The Hang Seng Index opened 63 points higher, reporting at 27,246 points. WUXI BIO expects a 46.3% increase in net profit last year, with its stock price opening 3.54% higher; SMIC reported a net profit of USD 173 million in the fourth quarter of last year, with its stock price opening 2.3% lower. In the U.S. stock market, the Dow Jones rose slightly, while the S&P 500 and Nasdaq fell. Tech stocks showed mixed performance, with Tencent down over 1% and Alibaba slightly up. Southbound funds net bought HKD 84.8 million in Hong Kong stocks

- U.S. stocks showed mixed results, with the Dow Jones reaching a record high of 50,512 points, closing up 52 points or 0.1%.  
- The S&P 500 fell 23 points or 0.33%, while the Nasdaq decreased by 135 points or 0.59%.  
- Major tech stocks like Tesla increased by 1.89%, whereas others like Alphabet and Amazon experienced declines.

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China Southern Hang Seng Biotech ETF(QDII)

Hwabao WP Hang Seng SCHK Innovative Drug Select ETF

Tianhong CNI BIOMEDICINE ETF

ChinaAMC CSI Biotechnology Theme ETF

Huaan Hang Seng Biotech ETF

China Merchants CSI Biotechnology Theme ETF

E Fund CSI 300 Health Care ETF

WUXI BIO

SMIC

ChinaAMC SSE STAR Biology and Medicine ETF

Guotai CSI Bio-medicine ETF

The Hang Seng Index opened 63 points higher, WUXI BIO rose 3.5% on positive earnings, and SMIC fell 2% | Hong Kong stock market opens