InSilico Medicine Wins China IND Nod for AI-Discovered IPF Drug Rentosertib

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2026.04.29 00:19
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InSilico Medicine has received Investigational New Drug approval from China's Center for Drug Evaluation for its inhaled solution Rentosertib, aimed at treating idiopathic pulmonary fibrosis. This is the 13th program from its AI-driven pipeline to reach clinical trials, highlighting the effectiveness of its Pharma.AI platform. The approval allows for a Phase I trial involving 80 subjects. Rentosertib, a small-molecule TNIK inhibitor, holds U.S. Orphan Drug and China Breakthrough Therapy Designations, potentially enhancing InSilico's position in AI-enabled drug discovery.