<div id="readability-page-1">ALISO VIEJO, Calif.--(BUSINESS WIRE)-- Ambry Genetics, a leader in clinical genomic testing, and a wholly owned subsidiary of Tempus AI, Inc. ( TEM ) , today announced that its CARE Program (Comprehensive, Assessment, Risk, and Education) has been awarded “Best Overall Health Informatics Solution” in the 10th Annual MedTech Breakthrough Awards. The global program recognizes excellence in digital health and medical technology, selecting CARE from more than 5,000 nominations worldwide. The CARE program is a best-in-class, EHR-integrated digital risk assessment program designed to help health systems identify patients at increased risk for breast cancer or who otherwise qualify for hereditary cancer testing. By utilizing a suite of digital tools embedded directly into existing clinical workflows, the CARE program identifies at-risk patients and provides them with personalized education while streamlining the entire genetic test ordering and results process for providers. This proactive approach helps clinicians understand a patient’s risk before the visit, enabling personalized care and earlier cancer detection through advanced screening. By directly connecting patients with certified genetic counselors, the program delivers an end‑to‑end model that makes genetic care more proactive, standardized, and equitable. “CARE has fundamentally changed how we care for patients at risk,” said Kevin M. Banks, Ph.D., Executive Director of Precision Health at The Christ Hospital Health Network. “It simplifies what used to be a 'process' by seamlessly integrating patient education and gives our clinicians critical insights when they matter most. CARE has not only smoothed our workflows but has also made a real difference in determining patient care.&#34; “Receiving this award alongside other industry leaders highlights the importance of integrating genetic insights directly into everyday clinical care to improve outcomes for high-risk patients,” said Tom Schoenherr, CEO of Diagnostics at Tempus. “CARE exemplifies Ambry’s commitment to streamlining clinical workflows and enabling providers to deliver more proactive, personalized care. We are incredibly proud of the impact CARE has already made, and will continue to make, in advancing care for high-risk patients.” About Ambry Genetics ® Ambry Genetics, a wholly owned subsidiary of Tempus, translates scientific research into clinically actionable test results based upon a deep understanding of the human genome and the biology behind genetic disease. It is a leader in genetic testing and aims to improve health by understanding the relationship between genetics and disease. Over its 25-year history, Ambry has remained committed to empowering patients to make informed healthcare decisions based on their genetic data. About TEMPUS ® Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of multimodal data, and an operating system to make that data accessible and useful, Tempus provides AI-enabled precision medicine solutions to physicians to deliver personalized patient care and in parallel facilitates discovery, development and delivery of optimal therapeutics. The goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as the company gathers more data. For more information, visit tempus.com. FORWARD LOOKING STATEMENTS This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended, about Tempus and Tempus’ industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, but not limited to, statements regarding the potential impact of Ambry Genetics research and publications; the contributions of Ambry Genetics research and findings to the larger scientific community and the use of its products and services to advance clinical care for patients are forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “going to,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” or “would” or the negative of these words or other similar terms or expressions. Tempus cautions you that the foregoing may not include all the forward-looking statements made in this press release. You should not rely on forward-looking statements as predictions of future events. Tempus has based the forward-looking statements contained in this press release primarily on its current expectations and projections about future events and trends that it believes may affect Tempus’ business, financial condition, results of operations and prospects. These forward-looking statements are subject to risks and uncertainties related to: Tempus’ financial performance; the ability to attract and retain customers and partners; managing Tempus’ growth and future expenses; competition and new market entrants; compliance with new laws, regulations and executive actions, including any evolving regulations in the artificial intelligence space; the ability to maintain, protect and enhance Tempus’ intellectual property; the ability to attract and retain qualified team members and key personnel; the ability to repay or refinance outstanding debt, or to access additional financing; future acquisitions, divestitures or investments; the potential adverse impact of climate change, natural disasters, health epidemics, macroeconomic conditions, and war or other armed conflict, as well as risks, uncertainties, and other factors described in the section titled “Risk Factors” in Tempus’ Annual Report on Form 10-K for the year ended December 31, 2025, filed with the Securities and Exchange Commission (“SEC”) on February 24, 2026, as well as in other filings Tempus may make with the SEC in the future. In addition, any forward-looking statements contained in this press release are based on assumptions that Tempus believes to be reasonable as of this date. Tempus undertakes no obligation to update any forward-looking statements to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law. <img src="https://imageproxy.pbkrs.com/https://cts.businesswire.com/ct/CT/query-ZGlzdHJvPW54JmlkPWJ3bmV3cyZsYW5nPWVuJnNpZD1hY3FyOCZzdHk9MjAyNjA1MTEyOTIzNTlyMQ?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" original-src="https://imageproxy.pbkrs.com/https://cts.businesswire.com/ct/CT/query-ZGlzdHJvPW54JmlkPWJ3bmV3cyZsYW5nPWVuJnNpZD1hY3FyOCZzdHk9MjAyNjA1MTEyOTIzNTlyMQ"/>View source version on businesswire.com: https://www.businesswire.com/news/home/20260511292359/en/ Source: Ambry Genetics</div>

Ambry Genetics’ CARE Program has won the 2026 MedTech Breakthrough Award for "Best Overall Health Informatics Solution." This award recognizes the program's excellence in digital health, selected from over 5,000 nominations. The CARE Program integrates digital risk assessment tools into clinical workflows to identify patients at risk for breast cancer and streamline genetic testing. It aims to enhance personalized care and early cancer detection. Ambry Genetics, a subsidiary of Tempus AI, focuses on translating genetic research into actionable healthcare solutions.

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Ambry Genetics’ CARE Program® Wins 2026 MedTech Breakthrough Award for “Best Overall Health Informatics Solution”