<p>/PRNewswire/ -- Duno Health, Inc.是一家領先的消費者健康科學公司，宣佈推出 Youth &amp; Vitality，這是一種新型日常補充劑，含有 NAD+ 前體和必需維生素，以支持細胞更新和全身健康。</p>
<p>繼續閲讀</p>
<p><img src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" alt="" original-src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null"/></p>
<p>產品描述</p>
<p><img src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" alt="" original-src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null"/></p>
<p>整個樣本人羣的離散分類變量之間的差異</p>
<p>現代研究：NAD+ 補充劑現在被認為是支持幾乎每個細胞代謝方面的一種方式，尤其對健康老齡化至關重要，因為 NAD+ 水平隨着年齡的增長而自然下降（表 1，1）。事實上，低 NAD+ 水平被認為是衰老的一個關鍵特徵，導致細胞代謝功能障礙、細胞衰老和免疫反應失調——即所謂的 “炎症老化”——並且與衰老相關的疾病有關。通過補充 NAD+ 前體來應對這種下降已成為老齡相關疾病預防和長壽領域的熱門話題，也是 Duno 的主要關注點。</p>
<p>臨牀測試結果：Youth &amp; Vitality 含有煙酰胺，這是一種 NAD+ 前體，已有數十年的臨牀試驗數據證明其在提高人類 NAD+ 水平方面的安全性和有效性。它還可以降低某些皮膚癌的風險，並改善一些炎症狀況（2）。通過將煙酰胺與關鍵的 B 族維生素結合，Youth &amp; Vitality 旨在促進細胞能量代謝和 DNA 修復，並支持包括心血管健康、神經保護、激素和性健康以及皮膚抗衰老效果在內的健康益處。</p>
<p>關注日常健康：心血管疾病是與年齡相關的疾病和醫療費用的主要原因，但專家認為大多數病例可以通過生活方式的改變來預防（3）。Youth &amp; Vitality 通過幫助降低同型半胱氨酸水平來支持心血管健康，這是一種被稱為心血管疾病風險生物標誌物的分子（4,5）。我們的配方包括維生素 B6、維生素 B12 和葉酸，這種組合已被證明可以顯著且協同地降低同型半胱氨酸水平（6）。</p>
<p>心血管健康與大腦健康以及發展神經退行性疾病或痴呆的風險密切相關，還與慢性腎病和勃起功能障礙等其他疾病相關。毫不奇怪，高同型半胱氨酸水平也與這些疾病相關（4,7,8），並被認為會加劇疾病進展的氧化應激。通過對抗高同型半胱氨酸水平，Youth &amp; Vitality 協同應對主要器官系統的衰老。</p>
<p>Youth &amp; Vitality 的配方基於最新的人類健康和長壽研究，旨在平衡每種成分的多方面益處。最近的臨牀前研究表明，維生素 B3 和 B6 可以刺激肌肉乾細胞擴展，並增強衰老過程中的再生能力（9）。還有證據表明，維生素 B6 和 B12 有助於增加睾酮的合成（10）。Duno Health 研究了衰老的關鍵特徵，涵蓋了從相互關聯的細胞通路到組織廣泛的影響，再到系統性疾病的機制。因此，該產品旨在支持細胞代謝的多個關鍵方面，並幫助控制同型半胱氨酸水平，為身體各個器官系統的健康功能奠定基礎，真正支持健康壽命。</p>
<p><strong>DUNO HEALTH 的 Youth &amp; Vitality 是特別設計和配方的多種維生素 B 混合物，支持臨牀研究的健康老齡化標誌：</strong></p>
<ul>
<li>提高 NAD+（煙酰胺腺嘌呤二核苷酸）</li>
<li>降低同型半胱氨酸（HCY）</li>
<li>刺激肌肉乾細胞擴展</li>
<li>促進性健康</li>
</ul>
<p><strong>如果您接近 50 歲或更大，定期監測和管理同型半胱氨酸水平可以在降低</strong> <strong>動脈粥樣硬化</strong> <strong>、</strong> <strong>血栓</strong> <strong>、</strong> <strong>心臟病發作</strong> <strong>、</strong> <strong>中風</strong> <strong>的風險以及支持長期健康方面發揮關鍵作用。</strong></p>
<p><strong>為了</strong> <strong>測試</strong> <strong>其有效性，請在服用補充劑的前一天和完成確切一個月（30 天）治療後的那一天抽血並測量同型半胱氨酸水平。提交您的兩個測試報告，購買另外兩瓶時將獲得 20 美元的折扣。該折扣有效期至 2026 年 8 月 31 日。</strong></p>
<p>有關更多詳細信息或購買和測試，請訪問 https://www.duno-health.com。聯繫電話：650-977-9992。</p>
<table>
<thead>
<tr>
<th></th>
</tr>
</thead>
<tbody>
<tr>
<td>參考文獻</td>
</tr>
<tr>
<td>1, PloS ONE, 2012, 7, e42357</td>
</tr>
<tr>
<td>2, 2a, Nature communications, DOI: 10.1038/ncomms12948；</td>
</tr>
<tr>
<td>2b, https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/</td>
</tr>
<tr>
<td>3, https://newsroom.clevelandclinic.org/2021/09/29/90-percent-of-heart-disease-is-preventable-through-healthier-diet-regular-exercise-and-not-smoking</td>
</tr>
<tr>
<td>4, N Engl J Med 2002;346:476-483; 4b,</td>
</tr>
<tr>
<td>5, https://medlineplus.gov/lab-tests/homocysteine-test/</td>
</tr>
<tr>
<td>6, 6a, Nutrition Research 2011, 31, 318-321</td>
</tr>
<tr>
<td>6b, https://pmc.ncbi.nlm.nih.gov/articles/PMC6529698/</td>
</tr>
<tr>
<td>7, Journal of Alzheimer's Disease 62 (2018) 561–570</td>
</tr>
<tr>
<td>8, J Prev Alz Dis 2021;3(8):329-334</td>
</tr>
<tr>
<td>9, J. Clin. Invest. 2024, 134, e163648</td>
</tr>
<tr>
<td>10, https://doi.org/10.5534/wjmh.240250</td>
</tr>
</tbody>
</table>
<p>來源 Duno Health</p>
<p><img src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjYwNTA4Jk5ld3NJdGVtSWQ9Q040OTk3MCZUcmFuc21pc3Npb25fSWQ9MjAyNjA1MDgxMDAwUFJfTkVXU19VU1BSX19fX19DTjQ5OTcw?x-oss-process=image/auto-orient,1/interlace,1/resize,w_1440,h_1440/quality,q_95/format,jpg" alt="" original-src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjYwNTA4Jk5ld3NJdGVtSWQ9Q040OTk3MCZUcmFuc21pc3Npb25fSWQ9MjAyNjA1MDgxMDAwUFJfTkVXU19VU1BSX19fX19DTjQ5OTcw"/></p>

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<p>Duno Health, Inc. 推出了一個新的日常補充劑，名為 Youth & Vitality，配方中含有 NAD+ 前體和必需維生素，以支持細胞更新和整體健康。該補充劑旨在通過提高 NAD+ 水平、降低同型半胱氨酸，並促進心血管和神經保護的好處來對抗與衰老相關的問題。它包含煙酰胺和關鍵的 B 維生素，這些成分經過臨牀測試，證明安全有效。該產品專為接近 50 歲的人羣設計，並提供血液檢測的促銷優惠，以測量效果</p>

<p>, /PRNewswire/ -- Duno Health, Inc., a leading consumer health sciences company, announced the launch of Youth &amp; Vitality, a new daily supplement formulated with NAD+ precursor and essential vitamins to support cellular renewal and whole body health.</p>
<div class="lb-trans"><p>/PRNewswire/ -- Duno Health, Inc.是一家領先的消費者健康科學公司，宣佈推出 Youth &amp; Vitality，這是一種新型日常補充劑，含有 NAD+ 前體和必需維生素，以支持細胞更新和全身健康。</p>
</div><p>Continue Reading</p>
<div class="lb-trans"><p>繼續閲讀</p>
</div><p><img src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null" alt="" original-src="https://www.prnewswire.com/news-releases/null"/></p>
<p>Product description</p>
<div class="lb-trans"><p>產品描述</p>
</div><p><img src="https://imageproxy.pbkrs.com/https://www.prnewswire.com/news-releases/null" alt="" original-src="https://www.prnewswire.com/news-releases/null"/></p>
<p>Differences between discrete categorised variable of the entire sample population</p>
<div class="lb-trans"><p>整個樣本人羣的離散分類變量之間的差異</p>
</div><p>Modern Age Research: NAD+ supplementation is now being recognized as a way to support almost every aspect of cellular metabolism, and can be especially important for healthy aging, since NAD+ levels naturally decline with age (Table 1, 1). In fact, low NAD+ levels are thought to be one of the key hallmarks of aging, contributing to dysfunctional cellular metabolism, cellular senescence, and dysregulated immune responses—so-called &#34;inflammaging&#34;—and have been found to be associated with aging-related disorders. Addressing this decline using supplementation with NAD+ precursors has become a hot topic in the aging-related disease prevention and longevity fields and is a primary focus for Duno.</p>
<div class="lb-trans"><p>現代研究：NAD+ 補充劑現在被認為是支持幾乎每個細胞代謝方面的一種方式，尤其對健康老齡化至關重要，因為 NAD+ 水平隨着年齡的增長而自然下降（表 1，1）。事實上，低 NAD+ 水平被認為是衰老的一個關鍵特徵，導致細胞代謝功能障礙、細胞衰老和免疫反應失調——即所謂的 “炎症老化”——並且與衰老相關的疾病有關。通過補充 NAD+ 前體來應對這種下降已成為老齡相關疾病預防和長壽領域的熱門話題，也是 Duno 的主要關注點。</p>
</div><p>Clinical Tested Results: Youth &amp; Vitality contains nicotinamide, a NAD+ precursor that has decades of clinical trial data showing its safety and effectiveness at boosting NAD+ levels in humans. It also functions in reducing the risk for certain skin cancers and in addressing some inflammatory conditions (2). By combining nicotinamide with key B vitamins, Youth &amp; Vitality aims to promote cellular energy metabolism and DNA repair, and to support health benefits including cardiovascular health, neuroprotection, hormonal and sexual health and anti-aging effects in the skin.</p>
<div class="lb-trans"><p>臨牀測試結果：Youth &amp; Vitality 含有煙酰胺，這是一種 NAD+ 前體，已有數十年的臨牀試驗數據證明其在提高人類 NAD+ 水平方面的安全性和有效性。它還可以降低某些皮膚癌的風險，並改善一些炎症狀況（2）。通過將煙酰胺與關鍵的 B 族維生素結合，Youth &amp; Vitality 旨在促進細胞能量代謝和 DNA 修復，並支持包括心血管健康、神經保護、激素和性健康以及皮膚抗衰老效果在內的健康益處。</p>
</div><p>Focus on Everyday health: Cardiovascular disease is a major cause of age-associated disease and healthcare costs, yet experts believe a majority of cases could be prevented by lifestyle changes (3). Youth &amp; Vitality supports cardiovascular health by helping to lower levels of homocysteine, a molecule known as a biomarker for cardiovascular disease risk (4,5). Our formula includes vitamin B6, vitamin B12, and folic acid, a combination that has been shown to significantly and synergistically reduce homocysteine levels (6).</p>
<div class="lb-trans"><p>關注日常健康：心血管疾病是與年齡相關的疾病和醫療費用的主要原因，但專家認為大多數病例可以通過生活方式的改變來預防（3）。Youth &amp; Vitality 通過幫助降低同型半胱氨酸水平來支持心血管健康，這是一種被稱為心血管疾病風險生物標誌物的分子（4,5）。我們的配方包括維生素 B6、維生素 B12 和葉酸，這種組合已被證明可以顯著且協同地降低同型半胱氨酸水平（6）。</p>
</div><p>Cardiovascular health is closely associated with brain health and risk of developing neurodegenerative disease or dementia, as well as other conditions such as chronic kidney disease and erectile dysfunction. Unsurprisingly, high homocysteine levels have also been associated with these diseases (4,7,8）, and are thought to contribute to oxidative stress that worsens the progression of disease. By combating high homocysteine levels, Youth &amp; Vitality synergistically addresses aging across major organ systems.</p>
<div class="lb-trans"><p>心血管健康與大腦健康以及發展神經退行性疾病或痴呆的風險密切相關，還與慢性腎病和勃起功能障礙等其他疾病相關。毫不奇怪，高同型半胱氨酸水平也與這些疾病相關（4,7,8），並被認為會加劇疾病進展的氧化應激。通過對抗高同型半胱氨酸水平，Youth &amp; Vitality 協同應對主要器官系統的衰老。</p>
</div><p>Youth &amp; Vitality is formulated based on the latest research into human health and longevity, to balance the multifaceted benefits of each ingredient. Recent preclinical studies have shown that vitamins B3 and B6 can stimulate muscle stem cell expansion and enhance regenerative capacity during aging (9). There is also evidence that vitamins B6 and B12 help to increase the synthesis of testosterone (10). Duno Health has studied the key hallmarks of aging across levels of analysis, from interconnected cellular pathways to tissue-wide effects to the mechanisms underlying systemic disease. Thus this product is designed to support multiple key aspects of cellular metabolism and help control homocysteine levels, creating the foundations of healthy function across the body's organ systems and truly support healthspan.</p>
<div class="lb-trans"><p>Youth &amp; Vitality 的配方基於最新的人類健康和長壽研究，旨在平衡每種成分的多方面益處。最近的臨牀前研究表明，維生素 B3 和 B6 可以刺激肌肉乾細胞擴展，並增強衰老過程中的再生能力（9）。還有證據表明，維生素 B6 和 B12 有助於增加睾酮的合成（10）。Duno Health 研究了衰老的關鍵特徵，涵蓋了從相互關聯的細胞通路到組織廣泛的影響，再到系統性疾病的機制。因此，該產品旨在支持細胞代謝的多個關鍵方面，並幫助控制同型半胱氨酸水平，為身體各個器官系統的健康功能奠定基礎，真正支持健康壽命。</p>
</div><p><strong>Youth &amp; Vitality from DUNO HEALTH is specially designed and formulated blend of muti-vitamins Bs support clinically studied markers of health aging:</strong></p>
<div class="lb-trans"><p><strong>DUNO HEALTH 的 Youth &amp; Vitality 是特別設計和配方的多種維生素 B 混合物，支持臨牀研究的健康老齡化標誌：</strong></p>
</div><ul>
<li>Boosting NAD+ (nicotinamide adenine dinucleotide)</li>
<li>Reducing HCY (homocysteine)</li>
<li>Stimulate muscle stem cell expansion</li>
<li>Promote sexual health</li>
</ul>
<div class="lb-trans"><ul>
<li>提高 NAD+（煙酰胺腺嘌呤二核苷酸）</li>
<li>降低同型半胱氨酸（HCY）</li>
<li>刺激肌肉乾細胞擴展</li>
<li>促進性健康</li>
</ul>
</div><p><strong>If you're approaching 50 or older, regular monitoring and management of homocysteine levels can play a key role in reducing risks of</strong> <strong>atherosclerosis</strong> <strong>,</strong> <strong>blood clots</strong> <strong>,</strong> <strong>Heart attack</strong> <strong>,</strong> <strong>Stroke</strong> <strong>, and supporting long-term health.</strong></p>
<div class="lb-trans"><p><strong>如果您接近 50 歲或更大，定期監測和管理同型半胱氨酸水平可以在降低</strong> <strong>動脈粥樣硬化</strong> <strong>、</strong> <strong>血栓</strong> <strong>、</strong> <strong>心臟病發作</strong> <strong>、</strong> <strong>中風</strong> <strong>的風險以及支持長期健康方面發揮關鍵作用。</strong></p>
</div><p><strong>To</strong> <strong>test</strong> <strong>its effectiveness, please have your blood drawn and homocysteine levels measured on the day before taking the supplement and the day after completing exactly one month</strong> <strong>（</strong> <strong>30 days</strong> <strong>）</strong> <strong>of treatment. Submit both of your test reports, and you will receive a $20 discount when purchasing two more bottles. This discount is valid until August 31, 2026.</strong></p>
<div class="lb-trans"><p><strong>為了</strong> <strong>測試</strong> <strong>其有效性，請在服用補充劑的前一天和完成確切一個月（30 天）治療後的那一天抽血並測量同型半胱氨酸水平。提交您的兩個測試報告，購買另外兩瓶時將獲得 20 美元的折扣。該折扣有效期至 2026 年 8 月 31 日。</strong></p>
</div><p>For more details or buy and test it, please visit https://www.duno-health.com. Contact Phone: 650-977-9992.</p>
<div class="lb-trans"><p>有關更多詳細信息或購買和測試，請訪問 https://www.duno-health.com。聯繫電話：650-977-9992。</p>
</div><table>
<thead>
<tr>
<th></th>
</tr>
</thead>
<tbody>
<tr>
<td>References</td>
</tr>
<tr>
<td>1, PloS ONE, 2012, 7, e42357</td>
</tr>
<tr>
<td>2, 2a, Nature communications, DOI: 10.1038/ncomms12948；</td>
</tr>
<tr>
<td>2b, https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/</td>
</tr>
<tr>
<td>3, https://newsroom.clevelandclinic.org/2021/09/29/90-percent-of-heart-disease-is-preventable-through-healthier-diet-regular-exercise-and-not-smoking</td>
</tr>
<tr>
<td>4, N Engl J Med 2002;346:476-483; 4b,</td>
</tr>
<tr>
<td>5, https://medlineplus.gov/lab-tests/homocysteine-test/</td>
</tr>
<tr>
<td>6, 6a, Nutrition Research 2011, 31, 318-321</td>
</tr>
<tr>
<td>6b, https://pmc.ncbi.nlm.nih.gov/articles/PMC6529698/</td>
</tr>
<tr>
<td>7, Journal of Alzheimer's Disease 62 (2018) 561–570</td>
</tr>
<tr>
<td>8, J Prev Alz Dis 2021;3(8):329-334</td>
</tr>
<tr>
<td>9, J. Clin. Invest. 2024, 134, e163648</td>
</tr>
<tr>
<td>10, https://doi.org/10.5534/wjmh.240250</td>
</tr>
</tbody>
</table>
<div class="lb-trans"><table>
<thead>
<tr>
<th></th>
</tr>
</thead>
<tbody>
<tr>
<td>參考文獻</td>
</tr>
<tr>
<td>1, PloS ONE, 2012, 7, e42357</td>
</tr>
<tr>
<td>2, 2a, Nature communications, DOI: 10.1038/ncomms12948；</td>
</tr>
<tr>
<td>2b, https://pmc.ncbi.nlm.nih.gov/articles/PMC4570055/</td>
</tr>
<tr>
<td>3, https://newsroom.clevelandclinic.org/2021/09/29/90-percent-of-heart-disease-is-preventable-through-healthier-diet-regular-exercise-and-not-smoking</td>
</tr>
<tr>
<td>4, N Engl J Med 2002;346:476-483; 4b,</td>
</tr>
<tr>
<td>5, https://medlineplus.gov/lab-tests/homocysteine-test/</td>
</tr>
<tr>
<td>6, 6a, Nutrition Research 2011, 31, 318-321</td>
</tr>
<tr>
<td>6b, https://pmc.ncbi.nlm.nih.gov/articles/PMC6529698/</td>
</tr>
<tr>
<td>7, Journal of Alzheimer's Disease 62 (2018) 561–570</td>
</tr>
<tr>
<td>8, J Prev Alz Dis 2021;3(8):329-334</td>
</tr>
<tr>
<td>9, J. Clin. Invest. 2024, 134, e163648</td>
</tr>
<tr>
<td>10, https://doi.org/10.5534/wjmh.240250</td>
</tr>
</tbody>
</table>
</div><p>SOURCE Duno Health</p>
<div class="lb-trans"><p>來源 Duno Health</p>
</div><p><img src="https://imageproxy.pbkrs.com/https://rt.prnewswire.com/rt.gif/query-RGF0ZUlkPTIwMjYwNTA4Jk5ld3NJdGVtSWQ9Q040OTk3MCZUcmFuc21pc3Npb25fSWQ9MjAyNjA1MDgxMDAwUFJfTkVXU19VU1BSX19fX19DTjQ5OTcw" alt="" original-src="https://rt.prnewswire.com/rt.gif?NewsItemId=CN49970&amp;Transmission_Id=202605081000PR_NEWS_USPR_____CN49970&amp;DateId=20260508"/></p>

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