SG#AKESORC2704A

AKESO to release FY2025 earnings report on March 26 During-Market (BJT), forecast revenue HKD 3.726 B, EPS HKD -0.3479

CanAngen's AK150 Receives Clinical Trial Approval

Nomura Adjusts Kanghong Biotech Revenue Forecast and Target Price

CanSino and Inovio Partner to Evaluate Efficacy in Glioblastoma Treatment

NMPA Approves Kangkang Biotech's AK139 to Enter Phase II Clinical Trials for 7 Indications

Kangkang Biologics Grants JinChuan Pharmaceutical Exclusive Commercialization Rights to Enoximab

CanSino Biologics' PD-1/VEGF Bi-specific Antibody Ivolimab Receives FDA Acceptance

CanSinoBio Updates Contract Manufacturing Arrangement with CTTQ-Akeso

BofA Securities Initiates Coverage of CanSino Biologics with a Buy Rating

Summit Submits BLA for Ivonescimab to FDA

Daiwa Downgrades Kangchen Biotech's Rating to 'Hold' and Adjusts Target Price

Konka Biotech Develops and Approves Global First Tumor Immune Bispecific Antibody Camrelizumab

China's Pharmaceutical Industry Transforms into a Global Innovation Hub

Cancer Biologics Kangdein Biotech Makes Multiple Progresses in Core Product Pipeline

Akeso Announces Significant Efficacy in Phase II Study of Cadonilimab for Resectable Gastric Cancer

CanSino Biologics Announces Latest Findings of HARMONi-6 Trial at 2025 ESMO Asia Congress

CanAngen's 5 self-developed new drugs successfully enter the National Medical Insurance Catalog

CITIC Securities Issues Positive Report on CanAngela's Pipeline

Competition Between Kangkang Biotech and Ssan Pharmaceutical in PD-1/VEGF Bispecific Antibodies

Akeso Announces Significant OS Improvement in Ivonescimab Study

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NEW VISION CO

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KAISA GROUP

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AOM INT'L

TRIO IND ELEC

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Hong Kong stocks are under pressure during the trading session, with all three major indices collectively declining, the Hang Seng Index and the Technology Index both down 1.87%. In terms of sectors, the internet and retailers are leading the decline, with Tencent Holdings falling over 6%, while Xiaomi Group, with a 3.41% increase, is leading against the trend. Market sentiment is cautious, with funds focusing on key price support levels, and the top three trading volumes are Tencent Holdings, Xiaomi Group, and Alibaba

- The Hong Kong stock market is under pressure, with the Hang Seng Index down 1.87% to 25,538.35, failing to reach new highs.  
- Major sectors, particularly internet and retail, are showing declines influenced by technology stocks, while macroeconomic data, especially unemployment rates, are drawing investor attention.  
- Notable stock movements include Tencent Holdings down 6.36% and Alibaba down 3.78%, amid increasing market caution and liquidity concerns.

Market Heartbeat

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BABA-W

SUNNY OPTICAL

JD-SW

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AKESO

LENOVO GROUP

Xiaomi Corporation

Tencent Holdings Limited

Tencent

Hong Kong stocks intraday | Three major indices fell, Tencent dropped over 6%, Xiaomi rose against the trend by 3.41%

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On March 18th, Hong Kong stocks closed today with the three major indices slightly higher, with the Hang Seng Index rising 0.61% to successfully return to 26,000 points. In terms of sectors, the retail sector performed strongly driven by consumer recovery, while the oil and gas sector declined due to fluctuations in oil prices. The heavyweight stock Alibaba rose 2.30%, supporting the index. The market was active, with significant movements in the artificial intelligence concept and optical fiber sectors, as funds speculated on the pace of economic recovery and key macro indicators

- On March 18, Hong Kong's stock indices saw slight gains while maintaining a volatile pattern, with overall market sentiment remaining stable.  
- The Hang Seng Index rose by 0.61% to 26,025.42 points, staying above 26,000 but still below previous highs, while the Hang Seng Tech Index increased marginally by 0.01%.  
- Retail stocks surged amid expectations of consumer recovery, whereas the oil and gas sector weakened due to international price fluctuations.

KINGSOFT CLOUD

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Hang Seng Index

Hong Kong stock market closing | Hang Seng Index rose 0.61% to stand above 26,000 points, with the retail sector leading the gains. Alibaba rose 2.3%

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During the trading session, the three major indices of the Hong Kong stock market maintained high-level fluctuations, with the Hang Seng Index down 0.04%, the Hang Seng TECH Index down 0.67%, and the Hang Seng China Enterprises Index down 0.40%, all failing to break through yesterday's highs, indicating a strong wait-and-see sentiment among investors. In terms of sectors, electronic components and internet content showed mixed performance, while retailers were boosted by certain companies. KB LAMINATES and Tencent Holdings saw active trading, with popular stocks such as Shanghai Fudan and ZTO EXPRESS showing significant gains, while the overall market turnover remained high and volatile

- On March 18, Hong Kong's stock indices showed weak fluctuations, with the Hang Seng Index at 25,858.35, down 0.04%.  
- Investors remained cautious, with limited significant macro data influencing the market; attention was focused on economic growth, inflation, and employment indicators.  
- Notable stocks included Shanghai Fudan, which rose 6.98%, and ZTO Express, which increased 4.76%, amidst a market environment characterized by cautious investor sentiment.

KB LAMINATES

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SHANGHAI FUDAN

ZTO EXPRESS-W

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China Southern Hang Seng ETF

Hang Seng TECH ETF I

TRACKER FUND

FI2 CSOP HSI

KINGBOARD HLDG

AXA SPDB CSI Hugangshen Game and Culture Media ETF

ChinaAMC Hang Seng ETF

Huatai-PB CSOP Hang Seng Technology ETF(QDII)

HSCEI ETF

FI CSOP HSI

Dacheng Hang Seng Technology ETF(QDII)

Hang Seng China Enterprises Index

FL2 CSOP HSI

CSOP HS TECH

Hang Seng TECH Index

Hong Kong Stock Market Intraday | Hang Seng Index fluctuates at a high level, MINIMAX-W rises 10.84%

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Akeso’s AK120 Phase II Completion Adds New Momentum to Its Atopic Dermatitis Pipeline

Tip Ranks

ICBCCS SSE STAR Biology and Medicine ETF

Bosera Hang Seng Health Care ETF(QDII)

ChinaAMC SSE Health Care ETF Initiating Fund

China Southern Hang Seng Biotech ETF(QDII)

Guotai CSI Bio-medicine ETF

Hwabao WP Hang Seng SCHK Innovative Drug Select ETF

Founder Fubon CSI Medicine and Medical Device Innovation ETF

ChinaAMC SSE STAR Biology and Medicine ETF

ChinaAMC Hang Seng Biotechnology Technology ETF(QDII)

E Fund CSI Biotechnology Theme ETF

E Fund Hang Seng SCHK Innovative Drug ETF

ChinaAMC CSI Biotechnology Theme ETF

E Fund CSI 300 Health Care ETF

Minsheng Royal CSI Biotechnology Theme ETF

Ping An CSI Medicine and Medical Device Innovation ETF

Fullgoal Hang Seng SCHK Innovative Drug & Healthcare ETF

Yinhua CSI Innovative Drugs Industry ETF

Tianhong CNI BIOMEDICINE ETF

Penghua SSE STAR Biology and Medicine ETF

Bosera Hang Seng SCHK Innovative Drug Select ETF

China Merchants CSI Biotechnology Theme ETF

Akeso’s AK120 Phase II Completion Adds New Momentum to Its Atopic Dermatitis Pipeline

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Akeso (SEHK:9926) has received IND clearance for its trispecific antibody AK150, allowing clinical trials for advanced solid tumors. This news coincided with a 5.81% one-day share price increase and a 12.44% return over seven days, with the current share price at HK$116.6. The company has a one-year total shareholder return of 62.96%. Analysts suggest a fair value of HK$172.49 per share, indicating potential undervaluation, but caution that high P/S ratios may reflect already priced-in success. Investors are advised to assess the stock's growth potential and risks.

Simplywall

Penghua CSI HK Connect Health Care Composite ETF

A Look At Akeso (SEHK:9926) Valuation After IND Clearance For Trispecific Antibody AK150

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Akeso, Inc. has announced that its trispecific antibody AK150 has received IND clearance for clinical trials targeting advanced solid tumors. This first-in-class antibody uniquely targets ILT2, ILT4, and CSF1R, aiming to enhance anti-tumor activity by modulating both innate and adaptive immune systems. AK150 shows promise in converting 'cold tumors' to 'hot tumors' and has demonstrated dose-dependent tumor inhibition in preclinical models. It represents a significant advancement in immunotherapy, addressing the limitations of existing single- or dual-target therapies.

marketscreener

Huaan Hang Seng Biotech ETF

Akeso Announces Trispecific Antibody AK150 Enters Clinical Trials

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The three major indices of the Hong Kong stock market strengthened collectively during the session, with the Hang Seng TECH Index rising by 0.92%, outperforming others. The internet content and information sector led the market, with Tencent Holdings rising by 1.81% and trading volume exceeding HKD 14 billion, ranking first. Overall market sentiment is relatively stable, but it is still in a confirmation period near previous highs, with clear signs of sector differentiation, as funds continue to flow towards leading internet companies and some new energy blue chips

- On March 11, during the trading session, Hong Kong's stock indices showed mixed strength, with the Hang Seng Index up 0.33% at 26,046 points.  
- The internet content sector led gains, driven by recovering demand, while the telecommunications equipment sector exhibited mixed performance.  
- Investors are closely monitoring macroeconomic indicators such as forex reserves and PMI, which continue to influence market sentiment amid fluctuations in retail and export data.

YOFC

NEWBORNTOWN

LINGBAO GOLD

CHIFENG GOLD

Tianhong Hang Seng TECH ETF(QDII)

ChinaAMC Hang Seng Technology ETF(QDII)

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HSTECH ETF

CAM HS TECH

ISHARESHSTECH

Hong Kong stocks intraday | The Tech Index rose 0.92%, with the internet sector leading the gains as Tencent climbed

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YOFC(06869) rose 24.33%, with a trading turnover 6.9 Billion HKD, and a year-to-date rose 242%. MINIMAX-WP(00100) rose 22.37%, with a trading turnover 4.3 Billion HKD, and a year-to-date rose 639.4%. CHALCO(02600) fell 3.58%, with a trading turnover 754.5 Million HKD, and a year-to-date rose 8.4%. PETROCHINA(00857) fell 3.57%, with a trading turnover 2.3 Billion HKD, and a year-to-date rose 22.4%.

Top Gainers & Losers

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KNOWLEDGE ATLAS

CHALCO

PETROCHINA

CHINA COAL

MUYUAN

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Top 5 HK Stock Gainers/Losers (>100B) (3.10)

AKESO rose 10.90%; Innovent Biologics rose 3.79%, with a transaction volume of HKD 404 million; 3SBio rose 5.48%, with a transaction volume of HKD 352 million; BeiGene rose 2.63%, with a transaction volume of HKD 309 million; Kelun-Bio rose 7.37%, with a market value of HKD 95.1 billion

HK Stock Movers Tracker

Hong Kong Stock Movement: AKESO's tri-specific antibody approved for clinical trials, stock price surges over 10%, attracting market attention

Jiahui International Cancer Center (JICC) in China has successfully stabilized a U.S. patient with advanced non-small cell lung cancer (NSCLC) using ivonescimab, a novel immunotherapy. The patient, who had previously exhausted all standard treatments, received care from a multidisciplinary team, including U.S.-trained oncologists. Despite developing complications requiring ICU care, the patient's condition has stabilized. JICC is gaining recognition as a global hub for advanced cancer care, attracting patients from around the world.

prnewswire

GF CSI HK Innovative Drugs Industry ETF(QDII)

23:20 ETU.S. Patient with Advanced Lung Cancer Stabilized by Novel Immunotherapy Treatment in China

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On March 6th, the Hong Kong stock market's risk appetite warmed up, with all three major indices strengthening, led by the Hang Seng Tech Index which rose by 3.15%. The retail and internet sectors showed strong momentum, with JD-SW leading the surge with a 9.95% increase, while Tencent Holdings had the highest trading volume and closed up by 3.39%. On the macro level, the rebound in PMI and the recovery in exports provided support for the fundamentals. Although the rebound momentum continues, the market is still focused on whether policies and liquidity can help break through previous highs

- The Hong Kong stock market saw overall gains, with the Hang Seng Index closing at 25,757.29 points, up by 1.72%.  
- Notable performances included JD.com surging 9.95% and Tencent gaining 3.39%, while mixed results emerged in specific sectors.  
- Market momentum is supported by improvements in macroeconomic indicators, driving investor confidence and attention towards future policy impacts on risk preferences.

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LEGENDHOLDING

REMEGEN

MENGNIU DAIRY

CH ENERGY ENG

CHINA RES LAND

Hong Kong stocks close | The Science and Technology Index leads with a 3.15% increase, JD rises nearly 10%, and both Tencent and Alibaba rise over 3%

SG#AKESORC2704A(54655.HK)

SG#AKESORC2704A Stock Performance Chart

Hong Kong stocks intraday | Three major indices fell, Tencent dropped over 6%, Xiaomi rose against the trend by 3.41%

Hong Kong stock market closing | Hang Seng Index rose 0.61% to stand above 26,000 points, with the retail sector leading the gains. Alibaba rose 2.3%

Hong Kong Stock Market Intraday | Hang Seng Index fluctuates at a high level, MINIMAX-W rises 10.84%

Akeso’s AK120 Phase II Completion Adds New Momentum to Its Atopic Dermatitis Pipeline

A Look At Akeso (SEHK:9926) Valuation After IND Clearance For Trispecific Antibody AK150