| Shareholder | |||||
|---|---|---|---|---|---|
FMR LLC | 10.30% | 19.52M | 3.75% | +8.88M | |
Redmile Group, LLC | 7.67% | 14.55M | 0.88% | +2.68M | |
BlackRock, Inc. | 7.14% | 13.54M | 0.41% | +2.60M | |
State Street Investment Management | 5.18% | 9.82M | 0.92% | +2.91M | |
Alerce Investment Management L.P. | 5.03% | 9.53M | 0.46% | +613.50K | |
BVF Partners L.P. | 4.59% | 8.70M | 0.76% | +0 | |
Vanguard Capital Management, LLC | 4.21% | 7.98M | <0.01% | +1.13M | |
Woodline Partners LP | 3.65% | 6.93M | 2.21% | +4.59M | |
MAK Capital One, LLC | 3.09% | 5.86M | 0.19% | +1.14M | |
Artal Group S.A. | 2.35% | 4.46M | 0.08% | +500.00K | |
Bain Capital Life Sciences Investors, LLC | 2.34% | 4.44M | 0.87% | -774.94K | |
Bellevue Asset Management AG | 2.16% | 4.10M | 1.01% | -1.06M | |
Geode Capital Management, LLC | 2.13% | 4.04M | 0.05% | +659.37K | |
MPM BioImpact LLC | 1.87% | 3.54M | -- | +3.54M | |
Columbia Management Investment Advisers, LLC | 1.85% | 3.51M | 0.27% | +60.50K | |
Great Point Partners, LLC | 1.85% | 3.50M | 0.31% | +1.00M | |
Adage Capital Management, L.P. | 1.85% | 3.50M | 0.80% | -800.00K | |
The Goldman Sachs Group, Inc. | 1.66% | 3.14M | 0.90% | +1.91M | |
Palo Alto Investors LP | 1.56% | 2.95M | 0.26% | +0 | |
Morgan Stanley | 1.50% | 2.84M | 0.15% | +158.04K |
